INT46293

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Context Info
Confidence 0.35
First Reported 1980
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.18
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Atp7a) transport (Atp7a) Golgi apparatus (Atp7a)
endoplasmic reticulum (Atp7a) mitochondrion organization (Atp7a) plasma membrane (Atp7a)
Anatomy Link Frequency
brain 1
Atp7a (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 6 100.00 Very High Very High Very High
noradrenaline 2 98.00 Very High Very High Very High
Pain 6 87.52 High High
Catecholamine 1 45.12 Quite Low
anesthesia 1 30.80 Quite Low
Disease Link Frequency Relevance Heat
Pain 6 87.52 High High
Muscular Spasm 2 86.80 High High
Hypertrophy 1 84.92 Quite High
Disease 1 84.52 Quite High
Cervical Cancer 1 79.52 Quite High
Hair Disease 1 77.84 Quite High
Dystonia 5 75.00 Quite High
Prolapse 1 75.00 Quite High
Injury 1 73.36 Quite High
Movement Disorders 1 63.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, Menkes protein mRNA levels were decreased in patients with cervical disc herniation (P = 0.03).
Negative_regulation (decreased) of Menkes protein
1) Confidence 0.35 Published 2002 Journal Mov. Disord. Section Abstract Doc Link 12210860 Disease Relevance 1.02 Pain Relevance 0.36
Noradrenaline concentrations are also reduced in brain tissue of Mo mice and this reduction is associated with a decrease in the vivo activity of the copper metalloenzyme, dopamine beta-monooxygenase (EC 1.14.17.1).
Negative_regulation (decrease) of EC 1.14.17.1 in brain associated with dopamine and noradrenaline
2) Confidence 0.09 Published 1980 Journal Ciba Found. Symp. Section Abstract Doc Link 6907087 Disease Relevance 0.16 Pain Relevance 0.34

General Comments

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