INT46334

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Context Info
Confidence 0.36
First Reported 1982
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 2.66
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (FOXC1) nucleus (FOXC1) DNA binding (FOXC1)
transcription factor binding (FOXC1) cytoplasm (FOXC1)
FOXC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 136 94.64 High High
agonist 48 89.52 High High
cytokine 160 79.64 Quite High
corticosteroid 8 73.36 Quite High
Crohn's disease 28 59.48 Quite High
Inflammatory response 8 38.80 Quite Low
Pain 1 25.00 Low Low
dexamethasone 28 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 5 99.98 Very High Very High Very High
INFLAMMATION 140 94.64 High High
Inflammatory Bowel Disease 128 84.48 Quite High
Recurrence 8 69.92 Quite High
Disease 32 65.04 Quite High
Targeted Disruption 4 50.48 Quite High
Adhesions 8 50.16 Quite High
Mucositis 4 38.40 Quite Low
Death 4 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A literature review provided two more cases of pancreatitis associated with Ara-c therapy in patients previously treated with L-asparaginase.
Ara Binding (associated) of associated with pancreatitis
1) Confidence 0.36 Published 1982 Journal Cancer Section Abstract Doc Link 6949626 Disease Relevance 0.45 Pain Relevance 0
In addition, we found clear differences between EPA and ARA, i.e., that some proteins were expressed higher after EPA (IL-6, IL-10, MIP-1?
ARA Spec (clear) Binding (differences) of
2) Confidence 0.05 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.66 Pain Relevance 0.24
Therefore, and because of differences in ability to compete with ARA for incorporation in tissue phospholipids [10, 11], it is probably easier to lower mucosal ARA levels by increasing fish oil intake than by increasing OA intake.
ARA Binding (compete) of
3) Confidence 0.05 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.88 Pain Relevance 0.17
For example, IL-6 protein expression was higher after EPA as compared to ARA, whereas NF-?
ARA Binding (compared) of
4) Confidence 0.05 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.37 Pain Relevance 0.19
binding affinities of EPA and ARA, which are about the same [51], while we used much lower EPA concentrations than ARA concentrations.
ARA Binding (affinities) of
5) Confidence 0.05 Published 2007 Journal Lipids Section Body Doc Link PMC2039812 Disease Relevance 0.30 Pain Relevance 0.39

General Comments

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