INT46407

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 1982
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 5.85
Pain Relevance 1.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (ATN1) nucleus (ATN1) cytoplasm (ATN1)
Anatomy Link Frequency
skin 2
ATN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 5 99.26 Very High Very High Very High
spondylitis 2 98.32 Very High Very High Very High
Inflammation 3 98.00 Very High Very High Very High
cytokine 1 97.08 Very High Very High Very High
Enkephalin 4 94.76 High High
substance P 3 93.92 High High
Neuropeptide 3 93.28 High High
Limbic system 1 87.36 High High
Neuropathic pain 13 85.76 High High
spinal inflammation 5 83.00 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 33 100.00 Very High Very High Very High
Genetic Predisposition To Disease 2 99.60 Very High Very High Very High
Psoriasis 5 99.26 Very High Very High Very High
Seronegative Spondarthritis 14 98.32 Very High Very High Very High
Parkinson's Disease 1 98.16 Very High Very High Very High
Syndrome 5 98.08 Very High Very High Very High
INFLAMMATION 2 98.00 Very High Very High Very High
Crystal Associated Disease 18 96.80 Very High Very High Very High
Uveitis 4 94.52 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 50 86.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When these crystals are deposited in synovial tissues, NLR proteins (NOD-like receptors) form multiprotein complexes known as inflammasomes that trigger secretion of inflammation-producing cytokines like interleukin-1?
NOD Binding (complexes) of associated with inflammation and cytokine
1) Confidence 0.36 Published 2010 Journal Metab. Clin. Exp. Section Abstract Doc Link 20837191 Disease Relevance 1.45 Pain Relevance 0.32
Based on these findings and previous reports, we conclude that (i) AAU is a manifestation of Bechterew's syndrome in HLA B27 positive patients, (ii) HLA B27 negative patients without any obvious accompanying manifestations may suffer from psoriatic spondylitis, and (iii) genetic predisposition to psoriasis in persons who are HLA B13, B17 and B37 negative, may interact with the genetic predisposition to Bechterew's syndrome in HLA B27 positive persons and produce Bechterew's syndrome with psoriasis or psoriasis-like skin eruptions.
B37 Binding (interact) of in skin associated with seronegative spondarthritis, psoriasis, spondylitis, syndrome, genetic predisposition to disease and uveitis
2) Confidence 0.35 Published 1982 Journal Clin. Genet. Section Abstract Doc Link 6980067 Disease Relevance 2.54 Pain Relevance 0.68
Other cytoarchitectural and myeloarchitectural techniques, specifically Nissl and Gallyas stainings, were used to delineate the boundaries of the ATN.
ATN Binding (boundaries) of
3) Confidence 0.28 Published 2007 Journal J Neural Transm Section Abstract Doc Link 17308982 Disease Relevance 0 Pain Relevance 0.54
Elevated serum lactate levels have been associated with ATN [9], and mitochondrial DNA levels in subcutaneous fat obtained by punch skin biopsies are also reduced after exposure to d4T and ddI [10].
ATN Binding (associated) of in skin associated with neuropathic pain
4) Confidence 0.08 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1919427 Disease Relevance 1.87 Pain Relevance 0.26

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox