INT46428

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Context Info
Confidence 0.23
First Reported 1982
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.36
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (LRRC23) cellular_component (LRRC23) biological_process (LRRC23)
LRRC23 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 48 100.00 Very High Very High Very High
Inflammation 30 98.24 Very High Very High Very High
spinal inflammation 4 90.96 High High
cytokine 11 67.64 Quite High
cINOD 6 5.00 Very Low Very Low Very Low
dexamethasone 5 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 98.24 Very High Very High Very High
Low Back Pain 4 90.96 High High
Death 3 40.24 Quite Low
Arthritis 6 5.00 Very Low Very Low Very Low
Atherosclerosis 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A monoclonal antibody that binds specifically to HLA-B27, B7, and B22 is described.
B7 Binding (binds) of
1) Confidence 0.23 Published 1982 Journal Hum. Immunol. Section Abstract Doc Link 6981636 Disease Relevance 0.08 Pain Relevance 0.08
Binding to B27 appeared to be slightly stronger than to B7 and stronger than to B22 in an indirect binding assay, but no difference in B7 and B27 binding could be detected by Scatchard analysis.
B7 Binding (binding) of
2) Confidence 0.15 Published 1982 Journal Hum. Immunol. Section Abstract Doc Link 6981636 Disease Relevance 0.09 Pain Relevance 0.14
Furthermore, the alteration to the aspirin structure in B15 and B7 likely contributed to their poor performance in this assay.
B7 Binding (alteration) of associated with aspirin
3) Confidence 0.11 Published 2008 Journal J Inflamm (Lond) Section Body Doc Link PMC2525633 Disease Relevance 0.19 Pain Relevance 0.39

General Comments

This test has worked.

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