INT46434

Context Info Confidence 0.16 First Reported 1982 Last Reported 1982 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0.54

peptidase activity (Prss12) extracellular region (Prl)

Anatomy Link Frequency third ventricle 2 Prss12 (Rattus norvegicus) Prl (Rattus norvegicus)

Pain Link Frequency Relevance Heat Serotonin 2 91.84 fluoxetine 4 84.88 Dopamine 4 81.12

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Neurotensin (NT) when injected in a dose of 5 micrograms into the third cerebral ventricle of conscious, unrestrained male rats, outfitted with chronic third ventricle and jugular cannulae, decreased the resting prolactin (PRL) levels.

NT Negative_regulation (decreased) of prolactin in third ventricle

1) Confidence 0.16 Published 1982 Journal Neuroendocrinology Section Abstract Doc Link 6983042 Disease Relevance 0 Pain Relevance 0.27

Neurotensin (NT) when injected in a dose of 5 micrograms into the third cerebral ventricle of conscious, unrestrained male rats, outfitted with chronic third ventricle and jugular cannulae, decreased the resting prolactin (PRL) levels.

NT Negative_regulation (decreased) of PRL in third ventricle

2) Confidence 0.16 Published 1982 Journal Neuroendocrinology Section Abstract Doc Link 6983042 Disease Relevance 0 Pain Relevance 0.27

General Comments

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