INT4651

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Context Info
Confidence 0.00
First Reported 1976
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 39
Total Number 39
Disease Relevance 20.19
Pain Relevance 8.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cebpz)
Anatomy Link Frequency
blood 6
macrophages 1
striatum 1
upper arm 1
Neuronal 1
Cebpz (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 44 100.00 Very High Very High Very High
Versed 18 99.98 Very High Very High Very High
isoflurane 27 99.60 Very High Very High Very High
imagery 195 99.56 Very High Very High Very High
Glutamate 19 99.36 Very High Very High Very High
alcohol 14 99.24 Very High Very High Very High
anesthesia 70 99.20 Very High Very High Very High
Adelta 1 98.58 Very High Very High Very High
Abeta 1 97.80 Very High Very High Very High
Acupuncture 6 97.54 Very High Very High Very High
Disease Link Frequency Relevance Heat
Ketoacidosis 847 100.00 Very High Very High Very High
Brain Injury 89 100.00 Very High Very High Very High
Hypotension 39 100.00 Very High Very High Very High
Depression 30 100.00 Very High Very High Very High
Fistula 19 100.00 Very High Very High Very High
Contusions 1 100.00 Very High Very High Very High
Pressure And Volume Under Development 454 99.86 Very High Very High Very High
Middle Cerebral Artery Infarction 24 99.84 Very High Very High Very High
Hypoxia 37 99.74 Very High Very High Very High
Injury 67 99.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 12 cases of the isoflurane group, no apparent rCBF and ECoG changes were seen, except a case with decreased rCBF and slow waves.
Gene_expression (changes) of rCBF associated with isoflurane
1) Confidence 0.00 Published 2010 Journal J Clin Neurophysiol Section Abstract Doc Link 20505374 Disease Relevance 0 Pain Relevance 0.42
Hypothermia in anesthetized and in ischemic-anesthetized rats did not significantly affect the levels of mitochondrial NADH, CBF and extracellular K(+).
Gene_expression (levels) of CBF associated with hypothermia
2) Confidence 0.60 Published 2002 Journal Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. Section Abstract Doc Link 12062215 Disease Relevance 0.72 Pain Relevance 0.14
CBF was calculated by the intracarotid 133Xenon method and CMRO2 as the product of CBF and the difference between systemic arterial and cerebral venous oxygen content.
Gene_expression (product) of CBF
3) Confidence 0.59 Published 1997 Journal Acta Neurol. Scand. Section Body Doc Link 9300074 Disease Relevance 0.09 Pain Relevance 0
Because of variations in DKA severity, however, mean initial CBF and ADC values for the different conditions studied also differed among experiments.
Gene_expression (values) of CBF associated with ketoacidosis
4) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2551666 Disease Relevance 1.09 Pain Relevance 0.08
Although bumetanide increased ADCs in DKA rats, it had no significant effect on CBF of cortex or striatum in DKA rats (Fig. 2B) or in control rats (1.48 ± 0.13 vs. 1.53 ± 0.13 ml · 100 g?
Gene_expression (cortex) of CBF in cortex associated with ketoacidosis
5) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2551666 Disease Relevance 0.44 Pain Relevance 0
Although bumetanide increased ADCs in DKA rats, it had no significant effect on CBF of cortex or striatum in DKA rats (Fig. 2B) or in control rats (1.48 ± 0.13 vs. 1.53 ± 0.13 ml · 100 g?
Gene_expression (rats) of CBF in striatum associated with ketoacidosis
6) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2551666 Disease Relevance 0.44 Pain Relevance 0
Although the reduced CBF values in most DKA rats were not in the range known to cause ischemic injury, it is likely that CBF reduction may reach these extremes only in the most severely ill animals.
Gene_expression (reduction) of CBF associated with ketoacidosis and injury
7) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2551666 Disease Relevance 2.25 Pain Relevance 0.08
Although the reduced CBF values in most DKA rats were not in the range known to cause ischemic injury, it is likely that CBF reduction may reach these extremes only in the most severely ill animals.
Gene_expression (values) of CBF associated with ketoacidosis and injury
8) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2551666 Disease Relevance 2.04 Pain Relevance 0.03
It is likely that this reduction in CBF is the result of multiple factors, including reduced circulatory volume due to dehydration and cerebral vasoconstriction caused by hypocapnia.
Gene_expression (reduction) of CBF associated with hypocapnia, volume depletion and dehydration and increased venous pressure under development
9) Confidence 0.58 Published 2008 Journal Diabetes Section Body Doc Link PMC2551666 Disease Relevance 2.19 Pain Relevance 0.08
RESULTS— CBF was significantly reduced in DKA and was responsive to alterations in pCO2.
Gene_expression (reduced) of CBF associated with ketoacidosis
10) Confidence 0.58 Published 2008 Journal Diabetes Section Abstract Doc Link PMC2551666 Disease Relevance 1.42 Pain Relevance 0.10
For the following 2 h, basal tpO(2) and CBF were reduced whereas basal CMRO(2) was persistently elevated by 8.1%+/-2.9%.
Gene_expression (reduced) of CBF
11) Confidence 0.57 Published 2009 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 19513087 Disease Relevance 1.14 Pain Relevance 0.50
Stimulation of the cheek, forepaw, upper arm and hindpaw produced significant increases in CBF, but stimulation of the other areas did not produce significant responses.
Gene_expression (produced) of CBF in upper arm
12) Confidence 0.53 Published 2003 Journal Am. J. Chin. Med. Section Abstract Doc Link 14587883 Disease Relevance 0 Pain Relevance 0
Microinjection of L-glutamate (50-100 nmol) into the septal complex also produced an increase in Hpc CBF.
Gene_expression (produced) of CBF associated with glutamate
13) Confidence 0.53 Published 1989 Journal Neurosci. Lett. Section Abstract Doc Link 2575724 Disease Relevance 0 Pain Relevance 0.22
Topical application of either NMDA or acetylcholine produced concentration-related increases in CBF.
Gene_expression (produced) of CBF
14) Confidence 0.52 Published 1998 Journal Neuroreport Section Abstract Doc Link 9512382 Disease Relevance 0.07 Pain Relevance 0.12
The FAIR technique was also able to detect the regional reduction in CBF produced by middle cerebral artery occlusion in rats.
Gene_expression (produced) of CBF in middle cerebral artery associated with middle cerebral artery infarction
15) Confidence 0.52 Published 1998 Journal Magn Reson Med Section Abstract Doc Link 9543418 Disease Relevance 0.10 Pain Relevance 0.12
The interaction of increased pressure and edema (AHP) produced the greatest decrease in CBF, although deep white flows were significantly affected in all experimental groups.
Gene_expression (produced) of CBF associated with pressure and volume under development
16) Confidence 0.52 Published 1976 Journal Stroke Section Abstract Doc Link 1258101 Disease Relevance 0.87 Pain Relevance 0.43
Furthermore, in the present study, passing of an electric current through acupuncture needles showed that excitation of group III (Adelta) and group IV (C) afferent fibers in the somatic nerve was capable of producing an increase in CBF, whereas excitation of group I (Aalpha) and group II (Abeta) fibers was ineffective.
Gene_expression (producing) of CBF in nerve associated with adelta, acupuncture and abeta
17) Confidence 0.51 Published 2000 Journal Jpn. J. Physiol. Section Abstract Doc Link 11120916 Disease Relevance 0 Pain Relevance 0.28
An infusion of beta-CCT given alone increased CMRO2 alone and reversed the depression in both cortical CBF and CMRO2 produced by midazolam plus alcohol.
Gene_expression (produced) of CBF associated with versed, depression and alcohol
18) Confidence 0.51 Published 1985 Journal Anesth. Analg. Section Abstract Doc Link 2857540 Disease Relevance 0.37 Pain Relevance 0.90
Midazolam infusions alone decreased cortical CBF and CMRO2 35-40%, while 2.5 mg/g alcohol (which did not depress CMRO2 alone) combined with midazolam produced a 70% depression of cortical CBF and metabolism.
Gene_expression (produced) of CBF associated with depression, versed and alcohol
19) Confidence 0.51 Published 1985 Journal Anesth. Analg. Section Abstract Doc Link 2857540 Disease Relevance 0.36 Pain Relevance 0.91
To examine whether these increased responses in cortical CBF produced by PBN were associated with the vasodilatation system of nitric oxide (NO), the NO synthase inhibitor L-NG-nitroarginine (L-NOArg), which is an analog of L-arginine, was used to inhibit the NO-related-vasodilatative system.
Gene_expression (produced) of CBF associated with increased venous pressure under development
20) Confidence 0.50 Published 1995 Journal Free Radic. Res. Section Abstract Doc Link 7544190 Disease Relevance 0.10 Pain Relevance 0.09

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