INT46722

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Context Info
Confidence 0.45
First Reported 1982
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 8
Total Number 9
Disease Relevance 4.84
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Csf2) extracellular region (Csf2)
Anatomy Link Frequency
blood 2
hypothalamus 2
CSF 2
lung 2
Csf2 (Mus musculus)
Pain Link Frequency Relevance Heat
Lasting pain 3 99.12 Very High Very High Very High
Inflammatory marker 1 97.76 Very High Very High Very High
Perioperative pain 2 96.28 Very High Very High Very High
metalloproteinase 16 94.64 High High
Inflammation 50 94.04 High High
ketamine 1 91.36 High High
cINOD 50 87.28 High High
Migraine 1 87.28 High High
Pain 6 83.92 Quite High
dexamethasone 45 81.44 Quite High
Disease Link Frequency Relevance Heat
Leukocytosis 4 100.00 Very High Very High Very High
Pulmonary Disease 5 99.82 Very High Very High Very High
Pain 9 99.12 Very High Very High Very High
Syndrome 4 97.84 Very High Very High Very High
INFLAMMATION 60 97.76 Very High Very High Very High
Appetite Loss 2 96.44 Very High Very High Very High
Post Operative Pain 2 96.28 Very High Very High Very High
Pulmonary Alveolar Proteinosis 34 94.64 High High
Cognitive Disorder 10 93.36 High High
Mycobacterial Infection 45 90.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As such, there were fewer changes in ARVD regimens in the GM-CSF group (19%) than in the placebo group (38%) for the lower viral load stratum (p = 0.03).
Regulation (changes) of Gene_expression (group) of GM-CSF
1) Confidence 0.45 Published 2005 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC1164429 Disease Relevance 0.36 Pain Relevance 0
The authors measured endorphin levels in the cerebrospinal fluid (CSF) of 12 patients with chronic pain due to lumbar disc syndrome and eight patients with acute postoperative pain.
Regulation (measured) of Gene_expression (levels) of CSF in CSF associated with syndrome, lasting pain and perioperative pain
2) Confidence 0.23 Published 1982 Journal Anesthesiology Section Abstract Doc Link 7091714 Disease Relevance 0.50 Pain Relevance 0.47
The relationship between CSF WCC and MMP-9 concentrations
Regulation (relationship) of Gene_expression (concentrations) of CSF WCC
3) Confidence 0.18 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2748711 Disease Relevance 0.09 Pain Relevance 0.27
To aspirate the CSF, the metal part of an insulin needle was adapted at one end of a polyethylene 50 tubing, and at the other end a 50 ?
Regulation (adapted) of Gene_expression (aspirate) of CSF
4) Confidence 0.17 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3022820 Disease Relevance 0.11 Pain Relevance 0.10
It would be helpful in the future to determine whether patients involved in trials experience changes in biomarkers in blood or CSF (such as A?
Spec (whether) Regulation (changes) of Gene_expression (blood) of CSF in blood
5) Confidence 0.11 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2893374 Disease Relevance 0.51 Pain Relevance 0.42
The slow progression and differences in severity of the lung disease between affected siblings with the same CSF2RA mutations and GM-CSF-R?
Regulation (affected) of Gene_expression (siblings) of GM-CSF in lung associated with pulmonary disease
6) Confidence 0.10 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2585845 Disease Relevance 0.87 Pain Relevance 0
In a recent study, Sinclair et al. showed that HAART despite treatment failures with no effect on peripheral viral load, had nevertheless a significant beneficial impact on CSF viral load, CSF pleocytosis, and immune activation [140].
Regulation (impact) of Gene_expression (pleocytosis) of CSF associated with leukocytosis
7) Confidence 0.09 Published 2010 Journal Retrovirology Section Body Doc Link PMC2864195 Disease Relevance 0.80 Pain Relevance 0.03
In a recent study, Sinclair et al. showed that HAART despite treatment failures with no effect on peripheral viral load, had nevertheless a significant beneficial impact on CSF viral load, CSF pleocytosis, and immune activation [140].
Regulation (impact) of Gene_expression (pleocytosis) of CSF associated with leukocytosis
8) Confidence 0.09 Published 2010 Journal Retrovirology Section Body Doc Link PMC2864195 Disease Relevance 0.80 Pain Relevance 0.03
It is abundant in choroid plexus where it modulates the production of cerebrospinal fluid (CSF), and in limbic regions and hypothalamus where it may play a role in motor behavior and appetite control.
Regulation (modulates) of Gene_expression (production) of CSF in hypothalamus associated with appetite loss
9) Confidence 0.04 Published 2003 Journal BMC Neurosci Section Body Doc Link PMC165579 Disease Relevance 0.81 Pain Relevance 0.12

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