INT46744

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Context Info
Confidence 0.47
First Reported 1982
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 1.66
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (HPR)
Anatomy Link Frequency
reticular formation 1
HPR (Homo sapiens)
Pain Link Frequency Relevance Heat
spinoreticular tract 3 99.48 Very High Very High Very High
Raphe 1 88.96 High High
Spinal cord 3 68.08 Quite High
Dorsal horn 1 54.80 Quite High
medulla 1 38.40 Quite Low
Thalamus 1 25.00 Low Low
nociceptor 1 25.00 Low Low
cytokine 42 5.00 Very Low Very Low Very Low
Inflammation 29 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 36 100.00 Very High Very High Very High
Targeted Disruption 9 95.20 Very High Very High Very High
Disease 104 92.16 High High
Infection 163 69.44 Quite High
Age-related Macular Degeneration 10 41.12 Quite Low
Cardiovascular Disease 12 37.92 Quite Low
Pulmonary Disease 2 34.48 Quite Low
Trypanosomiasis 93 5.00 Very Low Very Low Very Low
African Trypanosomiasis 66 5.00 Very Low Very Low Very Low
Parasitemia 42 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the Haptoglobin-related protein (HPR) is found in a CNV region that exhibits a higher copy number in the YRI individuals than in the individuals from the other two populations analyzed, and could be related to adaptation to sleeping sickness disease (see Discussion).
Gene_expression (found) of HPR associated with disease
1) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747275 Disease Relevance 0.15 Pain Relevance 0
For example, the Haptoglobin-related protein (HPR) is found in a CNV region that exhibits a higher copy number in the YRI individuals than in the individuals from the other two populations analyzed, and could be related to adaptation to sleeping sickness disease (see Discussion).
Gene_expression (found) of Haptoglobin-related protein associated with disease
2) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2747275 Disease Relevance 0.15 Pain Relevance 0
kDa high-density lipoprotein complex composed of apolipoprotein A-I (apoA-I), haptoglobin-related protein (Hpr), apoliprotein L-I (APOL1), human cathelicidin antimicrobial peptide (hCAP18), GPI-specific phospholipase D (GPI-PLD), apolipoprotein A-II, and paraoxanase [106, 110], and (ii) TLF2, a 1000?
Gene_expression (composed) of haptoglobin-related protein associated with disorder of lipid metabolism
3) Confidence 0.23 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2826769 Disease Relevance 0.46 Pain Relevance 0
Others have shown three human apolipoproteins (Hpr, APOA1, and APOL1) acting cooperatively for maximal killing capacity; however; the truncated APOL1 did not function in transgenic animal [118].
Gene_expression (shown) of Hpr associated with targeted disruption
4) Confidence 0.23 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2826769 Disease Relevance 0.44 Pain Relevance 0
kDa high-density lipoprotein complex composed of apolipoprotein A-I (apoA-I), haptoglobin-related protein (Hpr), apoliprotein L-I (APOL1), human cathelicidin antimicrobial peptide (hCAP18), GPI-specific phospholipase D (GPI-PLD), apolipoprotein A-II, and paraoxanase [106, 110], and (ii) TLF2, a 1000?
Gene_expression (composed) of Hpr associated with disorder of lipid metabolism
5) Confidence 0.23 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2826769 Disease Relevance 0.46 Pain Relevance 0
The distribution of the cells of origin of the primate spinoreticular tract was determined following injections of horseradish peroxidase (HPR) into the pontomedullary reticular formation in Macaca fascicularis.
Spec (determined) Gene_expression (injections) of HPR in reticular formation associated with spinoreticular tract
6) Confidence 0.22 Published 1982 Journal J. Comp. Neurol. Section Abstract Doc Link 7096639 Disease Relevance 0 Pain Relevance 0.19

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