INT46783

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Context Info
Confidence 0.15
First Reported 1982
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Abl2) cellular_component (Abl2) biological_process (Abl2)
Anatomy Link Frequency
paw 1
Abl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 9 100.00 Very High Very High Very High
Inflammation 3 98.40 Very High Very High Very High
intrathecal 3 97.52 Very High Very High Very High
Spinal cord 2 97.28 Very High Very High Very High
Spinal sensitization 1 75.00 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 98.40 Very High Very High Very High
Nociception 2 97.52 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study evaluated the role of nitric oxide (NO) in spinal cord nociceptive transmission during peripheral inflammation evoked by formalin injection into the rat paw, using N omega-nitro-L-arginine (N-Arg), an NO synthase inhibitor.
Negative_regulation (inhibitor) of N-Arg in paw associated with nociception, inflammation and spinal cord
1) Confidence 0.15 Published 1993 Journal Anesth. Analg. Section Abstract Doc Link 7692770 Disease Relevance 0.20 Pain Relevance 0.31
The only significant cross-reactivity was 30% with the reduced heptapeptide Met-enkephalin[Arg6,Phe7].
Negative_regulation (reduced) of Arg6 associated with enkephalin
2) Confidence 0.10 Published 1982 Journal J. Neurochem. Section Abstract Doc Link 7108539 Disease Relevance 0 Pain Relevance 0.65

General Comments

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