INT4686

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Context Info
Confidence 0.66
First Reported 1976
Last Reported 2010
Negated 1
Speculated 3
Reported most in Body
Documents 32
Total Number 35
Disease Relevance 36.24
Pain Relevance 2.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Cys1) cilium (Cys1) molecular_function (Cys1)
biological_process (Cys1) cytoplasm (Cys1)
Anatomy Link Frequency
muscle 4
blood 3
myocardium 1
Arm 1
posterior 1
Cys1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 249 99.36 Very High Very High Very High
Pain 23 99.12 Very High Very High Very High
cva 9 98.88 Very High Very High Very High
Inflammatory response 11 98.60 Very High Very High Very High
abdominal pain 5 97.52 Very High Very High Very High
anesthesia 14 95.68 Very High Very High Very High
isoflurane 7 95.56 Very High Very High Very High
Angina 40 93.28 High High
ischemia 125 88.40 High High
headache 4 78.56 Quite High
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 104 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 1 100.00 Very High Very High Very High
Myocardial Infarction 559 99.90 Very High Very High Very High
Muscle Weakness 12 99.90 Very High Very High Very High
Leptospirosis 5 99.84 Very High Very High Very High
Disease 144 99.62 Very High Very High Very High
Toxicity 52 99.50 Very High Very High Very High
Myalgia 22 99.44 Very High Very High Very High
INFLAMMATION 309 99.36 Very High Very High Very High
Hematuria 2 99.32 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found persistent (greater than 48 h) ECG changes in only 3, 2 of these 3 also had markedly elevated MB fraction of CPK.
Gene_expression (fraction) of CPK
1) Confidence 0.66 Published 1983 Journal Crit. Care Med. Section Abstract Doc Link 6861499 Disease Relevance 0.94 Pain Relevance 0.18
It appears that the use of antegrade cold intermittent blood cardioplegia with reperfusion is more optimal for myocardial protection, how show lower levels of CPK-MB especially in the first postoperative period.
Gene_expression (levels) of CPK-MB in blood
2) Confidence 0.59 Published 1995 Journal Acta Biomed Ateneo Parmense Section Abstract Doc Link 8928583 Disease Relevance 0.15 Pain Relevance 0
There were four perioperative myocardial infarctions as determined by ECG and CPK-MB levels, two in each group.
Spec (determined) Gene_expression (levels) of CPK-MB associated with myocardial infarction
3) Confidence 0.56 Published 1989 Journal Anesthesiology Section Abstract Doc Link 2563317 Disease Relevance 0.46 Pain Relevance 0.29
Cardiac troponin T and CPK MB levels remained in the normal range at repeat measurements.
Gene_expression (levels) of CPK MB
4) Confidence 0.54 Published 2009 Journal Clin Cardiol Section Abstract Doc Link 19382279 Disease Relevance 0.27 Pain Relevance 0.09
All 46 had physician diagnosis of acute myocardial infarction and CPK-MB was present in 44 (96%).
Gene_expression (present) of CPK-MB associated with myocardial infarction
5) Confidence 0.27 Published 1976 Journal Circulation Section Abstract Doc Link 1269133 Disease Relevance 0.42 Pain Relevance 0.08
It should be noted that the detectable CPK levels would not be above the normal range as determined for human whole blood samples.
Gene_expression (detectable) of CPK in blood associated with disorders of creatine metabolism
6) Confidence 0.17 Published 2003 Journal Crit Care Section Body Doc Link PMC374373 Disease Relevance 0.98 Pain Relevance 0.06
In this model, ischemic myocardium treated with IGF-1 had significantly lesser amounts of detectable CPK than did myocardium treated with TNF-?
Gene_expression (detectable) of CPK in myocardium associated with disorders of creatine metabolism
7) Confidence 0.17 Published 2003 Journal Crit Care Section Body Doc Link PMC374373 Disease Relevance 0.98 Pain Relevance 0.10
Robust inhibition of PKD was shown in the jck mouse model of slowly progressive disease as well as in the cpk mouse model of aggressive PKD.
Gene_expression (model) of cpk associated with disease
8) Confidence 0.16 Published 2007 Journal Cell Mol Life Sci Section Body Doc Link PMC2775119 Disease Relevance 0.65 Pain Relevance 0
Collected perfusate from hearts treated with IGF-1, at all reperfusion time points, contained significantly lower quantities of detectable CPK (34.6 U/l) than did perfusate from TNF-?
Gene_expression (detectable) of CPK in hearts associated with disorders of creatine metabolism
9) Confidence 0.15 Published 2003 Journal Crit Care Section Body Doc Link PMC374373 Disease Relevance 0.34 Pain Relevance 0.07
Muscle fasciculations, postoperative 24 hours myalgia, intubating conditions and levels of serum K+, CPK and DPH were recorded in every patient.
Gene_expression (levels) of CPK in Muscle associated with disorders of creatine metabolism, fasciculation and myalgia
10) Confidence 0.15 Published 1990 Journal Ma Zui Xue Za Zhi Section Abstract Doc Link 2277574 Disease Relevance 0.89 Pain Relevance 0.23
The ECG and the determination of serum enzymes creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) may be falsely normal early in acute myocardial infarction.
Gene_expression (determination) of CPK associated with disorders of creatine metabolism and myocardial infarction
11) Confidence 0.13 Published 1987 Journal Ann Emerg Med Section Abstract Doc Link 3619163 Disease Relevance 0.79 Pain Relevance 0.06
Presenting (0 hour) myoglobin determination was positive in 13 of 21 individuals, while CPK-MB was positive in only three.
Gene_expression (positive) of CPK-MB associated with disorders of creatine metabolism
12) Confidence 0.12 Published 1987 Journal Ann Emerg Med Section Abstract Doc Link 3619163 Disease Relevance 1.26 Pain Relevance 0.09
Evidence of a systemic inflammatory response and muscle involvement was observed commonly, manifested by elevated levels of C-reactive protein, creatine phosphokinase (CPK), lactate dehydrogenase (LDH), and aspartate aminotransferase (AST).
Gene_expression (levels) of CPK in muscle associated with inflammatory response and disorders of creatine metabolism
13) Confidence 0.09 Published 2010 Journal Emerging Infectious Diseases Section Body Doc Link PMC2874369 Disease Relevance 1.62 Pain Relevance 0.13
Comparison with healthy subjects was made by physical, ECG, echo-CG data, changes in the levels of creatinphosphokinase (MB-fraction) (CPK-MB), asparagine and alanine aminotransferase in the serum.
Gene_expression (levels) of CPK-MB
14) Confidence 0.08 Published 2002 Journal Klin Med (Mosk) Section Abstract Doc Link 12471834 Disease Relevance 0.56 Pain Relevance 0.03
Elevation of CPK levels was frequently observed in patients treated at our hospital, and elevation of CPK and AST levels suggest that muscle inflammation was present in these patients.
Gene_expression (levels) of CPK in muscle associated with inflammation and disorders of creatine metabolism
15) Confidence 0.08 Published 2010 Journal Emerging Infectious Diseases Section Body Doc Link PMC2874369 Disease Relevance 1.95 Pain Relevance 0.05
Elevation of CPK levels was frequently observed in patients treated at our hospital, and elevation of CPK and AST levels suggest that muscle inflammation was present in these patients.
Gene_expression (levels) of CPK in muscle associated with inflammation and disorders of creatine metabolism
16) Confidence 0.08 Published 2010 Journal Emerging Infectious Diseases Section Body Doc Link PMC2874369 Disease Relevance 2.03 Pain Relevance 0.05
STUDY OBJECTIVE: To determine if pretreatment with either gallamine or mivacurium before succinylcholine in children is associated with reduction in fasciculations; postoperative myalgias; or serum levels of potassium, creatinine phosphokinase (CPK), and myoglobin.
Gene_expression (levels) of CPK associated with fasciculation
17) Confidence 0.07 Published 2001 Journal J Clin Anesth Section Abstract Doc Link 11435054 Disease Relevance 0.10 Pain Relevance 0
Of note, elevated CPK levels were observed in patients with and without confirmed influenza virus infections.
Gene_expression (levels) of CPK associated with influenza virus infection and disorders of creatine metabolism
18) Confidence 0.07 Published 2010 Journal Emerging Infectious Diseases Section Body Doc Link PMC2874369 Disease Relevance 1.96 Pain Relevance 0.05
CPK elevation was more common in Arm B (45.0% of patients and 12.2% of cycles) than in Arm A (31.6% of patients, 8.4% of cycles).
Gene_expression (elevation) of CPK in Arm associated with disorders of creatine metabolism
19) Confidence 0.07 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2666889 Disease Relevance 2.07 Pain Relevance 0
The second most common cause was toxicity, which affected two (10.5%) and five (25.0%) patients (acute cardiomyopathy after 28 cycles ; muscular toxicity ; muscular weakness and CPK elevation, a combination of musculoskeletal cramps and CPK elevation ; a combination of grade 2 dyspnea, bronchial spams and atrial fibrillation ; three non-plitidepsin-related deaths).
Gene_expression (elevation) of CPK associated with cramps, toxicity, disorders of creatine metabolism, muscle weakness, arrhythmias 2 under development, dyspnea and coronary heart disease
20) Confidence 0.07 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2666889 Disease Relevance 1.03 Pain Relevance 0

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