INT47010

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Context Info
Confidence 0.43
First Reported 1982
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 4.16
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gusb) endoplasmic reticulum (Gusb) carbohydrate metabolic process (Gusb)
lysosome (Gusb)
Anatomy Link Frequency
coronary artery 1
Gusb (Mus musculus)
Pain Link Frequency Relevance Heat
depression 107 99.80 Very High Very High Very High
amygdala 1 97.32 Very High Very High Very High
anesthesia 11 94.64 High High
Analgesic 1 92.36 High High
Clonidine 6 91.52 High High
Inflammation 2 86.92 High High
Substantia nigra 1 50.40 Quite High
imagery 3 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Post-traumatic Stress Disorder 117 100.00 Very High Very High Very High
Heart Defects 45 100.00 Very High Very High Very High
Cv General 2 Under Development 4 100.00 Very High Very High Very High
Ventricular Heart Septal Defects 1 100.00 Very High Very High Very High
Depression 111 99.80 Very High Very High Very High
Hypothermia 1 96.40 Very High Very High Very High
Syndrome 3 95.32 Very High Very High Very High
Mitral Valve Stenosis 1 91.40 High High
Pressure And Volume Under Development 2 89.88 High High
INFLAMMATION 2 86.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antiproteolytic ability and beta-glucuronidase inhibition have been studied.
Negative_regulation (inhibition) of beta-glucuronidase
1) Confidence 0.43 Published 1996 Journal Arzneimittelforschung Section Abstract Doc Link 9125283 Disease Relevance 0.34 Pain Relevance 0.17
Hydralazine (but not other drugs) decreased GUR in the n. parabrachialis ventralis, n. centromedianus, n. reticularis medialis and n. suprachiasmaticus.
Negative_regulation (decreased) of GUR
2) Confidence 0.36 Published 1982 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 7176220 Disease Relevance 0.24 Pain Relevance 0.39
Closure of ASD was successfully achieved with an Amplatzer atrial septal occluder under transthoracic echocardiogram (TTE) guidance without general anesthesia.
Negative_regulation (Closure) of ASD associated with anesthesia and cv general 2 under development
3) Confidence 0.24 Published 2008 Journal J Coll Physicians Surg Pak Section Abstract Doc Link 18454897 Disease Relevance 0.63 Pain Relevance 0.09
This was the case; memory specificity predicted both PTSD and depression over and above initial ASD and depression diagnoses, ?
Negative_regulation (above) of ASD associated with post-traumatic stress disorder and depression
4) Confidence 0.22 Published 2008 Journal J Consult Clin Psychol Section Body Doc Link PMC2672050 Disease Relevance 1.80 Pain Relevance 0.40
The open heart surgery like coronary artery bypass graft (CABG), repair of ventricular septal defect (VSD) and atrial septal defect (ASD), valve replacement need a circulatory arrest, which is normally safe under conventional hypothermia.
Negative_regulation (repair) of ASD in coronary artery associated with hypothermia, cv general 2 under development and ventricular heart septal defects
5) Confidence 0.13 Published 2009 Journal Mymensingh Med J Section Abstract Doc Link 19377437 Disease Relevance 0.37 Pain Relevance 0.15
Serum levels of ANPN have been higher than in matched controls up to 35 years after surgical closure of ASD [37].
Negative_regulation (closure) of ASD associated with heart defects
6) Confidence 0.04 Published 2010 Journal International Journal of Pediatrics Section Body Doc Link PMC2859410 Disease Relevance 0.78 Pain Relevance 0

General Comments

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