INT47038

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 1980
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 14
Total Number 15
Disease Relevance 9.60
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SFRP1) extracellular space (SFRP1) extracellular region (SFRP1)
proteinaceous extracellular matrix (SFRP1) plasma membrane (SFRP1) intracellular (SFRP1)
Anatomy Link Frequency
muscle 4
bladder 1
SFRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 15 100.00 Very High Very High Very High
halothane 8 99.98 Very High Very High Very High
Pain 32 92.72 High High
vincristine 2 60.12 Quite High
cINOD 27 48.96 Quite Low
agonist 9 44.80 Quite Low
lumbar region 16 43.04 Quite Low
Kinase C 12 37.72 Quite Low
anesthesia 1 25.00 Low Low
backache 40 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Radiation Pneumonitis 144 100.00 Very High Very High Very High
Fatigue 256 99.98 Very High Very High Very High
Adenocarcinoma 72 99.32 Very High Very High Very High
Bladder Cancer 3 99.32 Very High Very High Very High
Cancer 352 96.88 Very High Very High Very High
Endometroid Carcinoma 21 96.48 Very High Very High Very High
Cervical Cancer 2 96.12 Very High Very High Very High
Hypocapnia 5 95.80 Very High Very High Very High
Breast Cancer 8 95.08 Very High Very High Very High
Stomach Cancer 2 94.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The FRP may very well be explained in light of the NNZ model.
Gene_expression (explained) of FRP
1) Confidence 0.67 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2850324 Disease Relevance 0.05 Pain Relevance 0
We recommend that criteria based upon relatively large differences in muscle activation should be considered when defining the FRP.
Gene_expression (defining) of FRP in muscle
2) Confidence 0.66 Published 2009 Journal J Electromyogr Kinesiol Section Abstract Doc Link 18586519 Disease Relevance 0.06 Pain Relevance 0.16
Our results revealed that lumbar muscle fatigue was appropriately produced prior to the FRP tasks.
Gene_expression (produced) of FRP in muscle associated with fatigue
3) Confidence 0.56 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2259346 Disease Relevance 0.72 Pain Relevance 0
We found a significant effect of muscular fatigue on both FRP cessation and FRP onset angles for all muscles (Figure 3).
Gene_expression (cessation) of FRP in muscles associated with fatigue
4) Confidence 0.56 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2259346 Disease Relevance 0.37 Pain Relevance 0
All participants expressed a cervical FRP as defined initially and as presented in Figure 2.
Gene_expression (expressed) of FRP
5) Confidence 0.53 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2850324 Disease Relevance 0 Pain Relevance 0
Thirteen of the analyzed loci showed statistically significant differences in DNA methylation when AD samples were compared to all NTL samples: OPCML, CDX2, HOXA1, CDKN2A EX2, SFRP1, CDH13, TWIST1, LZTS1, RASSF1, SFRP4 and 5, ESR1, and CDH1.
Gene_expression (samples) of SFRP1 associated with adenocarcinoma
6) Confidence 0.52 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2206053 Disease Relevance 1.18 Pain Relevance 0
Similarly to our findings, this augmented silent period was produced from both a reduction in onset angle of the FRP and a decreased FRP cessation angle.
Gene_expression (produced) of FRP
7) Confidence 0.49 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2259346 Disease Relevance 0.70 Pain Relevance 0
Westin and colleague [14] described that expression of estrogen-induced genes, RALDH2, EIG121, SFRP1, SFRP4, IGF-1, and IGF-IR, tend to be highest in the well-to-moderately differentiated endometrioid carcinoma.
Gene_expression (expression) of SFRP1 associated with endometroid carcinoma
8) Confidence 0.45 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 0.99 Pain Relevance 0
These results indicated that lumbar muscle fatigue produced a shift on the FRP, appearing sooner during flexion movement and later during extension movement.
Gene_expression (produced) of FRP in muscle associated with fatigue
9) Confidence 0.44 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2259346 Disease Relevance 0.59 Pain Relevance 0
Loss of expression of sFRP1 was reported in bladder cancer [55], and down-regulation of family members has been reported in cervical carcinomas [56], breast cancers [57], and gastric cancers [58], whilst the promoters of several sFRP family members have been shown to be hypermethylated in colorectal tumors [59–61].
Gene_expression (expression) of sFRP1 in bladder associated with colorectal cancer, cervical cancer, breast cancer, bladder cancer and stomach cancer
10) Confidence 0.39 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 1.55 Pain Relevance 0.08
Cancer cell growth may be inhibited by an agent that would selectively inhibit the binding of the Wnt protein with its Fzd receptor or which would upregulate the expression of endogenous antagonists such as sFRP,WIF-1, Cerberus or DKK.
Gene_expression (expression) of sFRP,WIF-1 associated with cancer and antagonist
11) Confidence 0.34 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.87 Pain Relevance 0.05
Of the 94 patients, 11 (11.7%) develop SARP; 6 (6.4%), grade 3; 2(2.1%), grade 4; and 3 (3.2%) grade 5.
Gene_expression (develop) of SARP associated with radiation pneumonitis
12) Confidence 0.23 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2883984 Disease Relevance 0.91 Pain Relevance 0
Table 4 shows the association between the dosimetric Parameters (NTCP/V10) and the incidence of SARP for 94 patients; the incidences of SARP in the group with NTCP > 4.2% and NTCP ?
Gene_expression (incidence) of SARP associated with radiation pneumonitis
13) Confidence 0.23 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2883984 Disease Relevance 1.12 Pain Relevance 0
WNT signals are context-dependently transduced to both pathways based on the expression profile of WNT, SFRP, WIF, DKK, Frizzled receptors, coreceptors, and the activity of intracellular WNT signaling regulators.
Gene_expression (expression) of SFRP
14) Confidence 0.17 Published 2007 Journal Clin. Cancer Res. Section Abstract Doc Link 17634527 Disease Relevance 0.08 Pain Relevance 0
Halothane prolonged the atrial functional (AtFRP), atrial effective (AtERP), and AV nodal functional refractory (AVFRP) periods.
Gene_expression (prolonged) of AtFRP associated with halothane
15) Confidence 0.00 Published 1980 Journal Anesth. Analg. Section Abstract Doc Link 7191673 Disease Relevance 0.41 Pain Relevance 0.35

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox