INT47387

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Context Info
Confidence 0.26
First Reported 1981
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GOT1) small molecule metabolic process (GOT1) biosynthetic process (GOT1)
carbohydrate metabolic process (GOT1) cellular nitrogen compound metabolic process (GOT1) lysosome (GOT1)
GOT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 2 100.00 Very High Very High Very High
Pain 1 97.56 Very High Very High Very High
Spinal cord 1 89.84 High High
opioid receptor 2 76.64 Quite High
Inflammation 1 75.08 Quite High
antagonist 1 73.04 Quite High
Opioid 1 72.60 Quite High
Disease Link Frequency Relevance Heat
Anorexia 1 98.92 Very High Very High Very High
Pain 1 97.56 Very High Very High Very High
Increased Venous Pressure Under Development 1 96.40 Very High Very High Very High
Poisoning 1 92.56 High High
Heart Rate Under Development 1 89.44 High High
Pressure Volume 2 Under Development 1 88.80 High High
Necrosis 1 88.40 High High
Sepsis 4 81.36 Quite High
INFLAMMATION 1 75.08 Quite High
Toxicity 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was decrease in the level of total protein and calcium and an increase of glutamic oxaloacetic transaminase (GOT), ammonia, sodium and potassium in serum.
Negative_regulation (decrease) of Positive_regulation (increase) of glutamic oxaloacetic transaminase
1) Confidence 0.26 Published 1981 Journal Vet Hum Toxicol Section Abstract Doc Link 7336560 Disease Relevance 0.45 Pain Relevance 0.14
Naltrexone significantly reduced the elevation of serum glutamate-oxalacetate transaminase and glutamate-pyruvate transaminase (as index of hepatic function) induced by LPS.
Negative_regulation (reduced) of Positive_regulation (elevation) of glutamate-oxalacetate transaminase associated with glutamate
2) Confidence 0.01 Published 2005 Journal J. Biomed. Sci. Section Abstract Doc Link 15917999 Disease Relevance 0.59 Pain Relevance 0.28

General Comments

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