INT47528

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Context Info
Confidence 0.29
First Reported 1980
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.47
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (GFER) mitochondrion (GFER) oxidoreductase activity (GFER)
extracellular region (GFER) cellular_component (GFER) cytoplasm (GFER)
Anatomy Link Frequency
skin 1
ventral 1
GFER (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 4 99.08 Very High Very High Very High
Morphine 2 97.80 Very High Very High Very High
nociceptor 4 94.80 High High
Mechanotransduction 1 57.60 Quite High
Disease Link Frequency Relevance Heat
Keloid Scars 13 100.00 Very High Very High Very High
Disease 5 99.28 Very High Very High Very High
Cicatrix 1 96.00 Very High Very High Very High
Stress 1 79.48 Quite High
Adhesions 1 52.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, I hypothesize that FPDs of the skin, including keloids and HSs, are the result of an excessive responsiveness or functional failure of either dermal cell mechanoreceptors (mechanosensors) or mechanosensitive nociceptors of sensory fibers in the skin.
Regulation (result) of HSs in skin associated with nociceptor, keloid scars and disease
1) Confidence 0.29 Published 2008 Journal Med. Hypotheses Section Abstract Doc Link 18614294 Disease Relevance 1.47 Pain Relevance 0.28
Rats trained on ventral tegmental intracranial self-stimulation (ICSS) were unaffected by acute injection of naloxone (2 mg/kg), while acute morphine (5 mg/kg) increased ICSS rate by 46%.
Neg (unaffected) Regulation (unaffected) of intracranial self-stimulation in ventral associated with narcan and morphine
2) Confidence 0.15 Published 1980 Journal Eur. J. Pharmacol. Section Abstract Doc Link 7408948 Disease Relevance 0 Pain Relevance 0.30

General Comments

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