INT47684

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Context Info
Confidence 0.59
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.66
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf)
Anatomy Link Frequency
hippocampus 2
Bdnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 8 99.68 Very High Very High Very High
antidepressant 5 99.64 Very High Very High Very High
cocaine 1 94.64 High High
Morphine 1 94.28 High High
Desipramine 1 86.16 High High
metalloproteinase 16 83.88 Quite High
Pyramidal cell 1 67.88 Quite High
ischemia 6 60.64 Quite High
Central nervous system 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 14 99.28 Very High Very High Very High
Stress 4 98.20 Very High Very High Very High
Neurodegenerative Disease 3 97.88 Very High Very High Very High
Injury 8 95.80 Very High Very High Very High
Apoptosis 8 94.04 High High
Death 14 93.52 High High
Hyperoxia 15 91.44 High High
Cv General 4 Under Development 2 60.64 Quite High
Hypoxia 39 52.00 Quite High
Cv Unclassified Under Development 4 51.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, chronic administration of ECS or antidepressant drugs completely blocked the down-regulation of BDNF mRNA in the hippocampus in response to restraint stress.
Negative_regulation (blocked) of Negative_regulation (down-regulation) of BDNF mRNA in hippocampus associated with stress, antidepressant, convulsion and hippocampus
1) Confidence 0.59 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7472505 Disease Relevance 0.80 Pain Relevance 0.51
The rise in BDNF after HI is attenuated if supplementary oxygen is used for resuscitation
Negative_regulation (attenuated) of Negative_regulation (rise) of BDNF
2) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3000320 Disease Relevance 0.86 Pain Relevance 0.15

General Comments

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