INT47745

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Context Info
Confidence 0.33
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc6a4, Htr2a) plasma membrane (Slc6a4, Htr2a) endosome (Slc6a4)
aging (Htr2a) response to stress (Htr2a) cytoplasm (Htr2a)
Slc6a4 (Rattus norvegicus)
Htr2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 3 100.00 Very High Very High Very High
antagonist 1 99.92 Very High Very High Very High
antidepressant 4 96.72 Very High Very High Very High
depression 1 93.24 High High
monoamine 1 86.48 High High
sSRI 2 84.84 Quite High
fluoxetine 2 28.64 Quite Low
Disease Link Frequency Relevance Heat
Depression 1 93.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies have shown that nefazodone is a potent antagonist of 5-HT2A receptors and binds to the serotonin transporter in vitro and in vivo.
serotonin transporter Binding (binds) of 5-HT2A associated with antagonist and serotonin
1) Confidence 0.33 Published 1995 Journal Life Sci. Section Abstract Doc Link 7475971 Disease Relevance 0.09 Pain Relevance 0.52

General Comments

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