INT47757

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.16
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CA2) extracellular space (CA2) lyase activity (CA2)
response to stress (CA2) cytoplasm (CA2)
Anatomy Link Frequency
neuronal 1
hippocampus 1
CA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 7 98.64 Very High Very High Very High
long-term potentiation 3 94.88 High High
Hippocampus 2 93.56 High High
nMDA receptor antagonist 1 93.04 High High
TRP channel 8 92.44 High High
Opioid 1 91.80 High High
Inflammation 31 86.64 High High
cytokine 13 86.00 High High
addiction 5 81.68 Quite High
Prostatitis 68 77.68 Quite High
Disease Link Frequency Relevance Heat
Disease 65 95.28 Very High Very High Very High
Cognitive Disorder 4 95.04 Very High Very High Very High
INFLAMMATION 33 86.64 High High
Bacterial Infection 23 84.40 Quite High
Prostatitis 68 77.68 Quite High
Targeted Disruption 2 74.48 Quite High
Convulsion 1 73.20 Quite High
Toxicity 12 50.80 Quite High
Alzheimer's Dementia 23 50.00 Quite Low
Apoptosis 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We report here that at short time periods (1-6 h) after injections of NMDA or sin-1 molsidomine, there is an increase in the levels of the mRNA encoding the alpha subunit of Ca2+/calmodulin-dependent protein kinase II (CaMKII alpha), consistent with a report of elevated CaMKII alpha mRNA in postsynaptic neurons in the CA1 region of the hippocampus following LTP induction [54].
Transcription (levels) of Ca2 in hippocampus associated with long-term potentiation and hippocampus
1) Confidence 0.67 Published 1995 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 7476022 Disease Relevance 0 Pain Relevance 0.28
As shown in Figure 3B and 3C, mRNA and protein expression of CFTR and CAII were significantly up-regulated upon stimulation of E.coli-LPS, respectively.
Transcription (expression) of CAII
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2998414 Disease Relevance 0.63 Pain Relevance 0.39
More indirect evidence that supports this idea is the enhancement of Ca2+ and K+ ion channel activity that has been observed in rodent cortical neuronal cultures upon application of soluble forms of A?
Transcription (activity) of Ca2 in neuronal
3) Confidence 0.21 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656296 Disease Relevance 0.53 Pain Relevance 0.05
Addition of Ca2+ after activation by 4?
Transcription (Addition) of Ca2
4) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.09
Ca2+-dependent facilitation has also been described for TRPC5 [26], TRPV3 [8], TRPV6 [9] and TRPA1 [27], [28].
Transcription (described) of Ca2
5) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox