INT47895

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Context Info
Confidence 0.22
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.35
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gk) histone binding (Gk) nucleus (Gk)
carbohydrate metabolic process (Gk) cytoplasm (Gk)
Anatomy Link Frequency
pancreas 1
smooth muscle cells 1
Gk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 1 98.72 Very High Very High Very High
Opioid 1 98.46 Very High Very High Very High
Somatostatin 1 97.18 Very High Very High Very High
fibrosis 14 85.12 High High
adenocard 1 84.24 Quite High
Inflammation 3 78.96 Quite High
potassium channel 1 75.00 Quite High
tolerance 2 44.72 Quite Low
anesthesia 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 166 100.00 Very High Very High Very High
Myocardial Infarction 78 93.36 High High
Apoptosis 62 90.28 High High
Fibrosis 12 85.12 High High
Hypertrophy 14 83.20 Quite High
Ganglion Cysts 3 82.32 Quite High
INFLAMMATION 3 78.96 Quite High
Stress 12 77.16 Quite High
Body Weight 2 56.60 Quite High
Cardiovascular Disorder Under Development 2 49.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sirt1 protein overexpression was further associated with a decrease in p53 acetylation in GK rats postligation.
Localization (postligation) of GK
1) Confidence 0.22 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2835668 Disease Relevance 1.59 Pain Relevance 0.15
Because similar transduction mechanisms are utilized by various membrane receptors, such as somatostatin, 5-hydroxytryptamine-1, alpha 2-adrenergic, mu-and delta-opioid, D2-dopamine, and gamma-aminobutyric acid B receptors, in neuronal, hormone-secreting, renal, or smooth muscle cells, the G protein (GK)-KACh channel system illustrates the principles underlying one of the most important cell signaling mechanisms (B.
Localization (secreting) of GK in smooth muscle cells associated with dopamine, somatostatin and opioid
2) Confidence 0.11 Published 1995 Journal Am. J. Physiol. Section Abstract Doc Link 7485449 Disease Relevance 0 Pain Relevance 0.28
The pancreas of Wistar diabetic (a model of type 1 diabetes) and GK (a model of type 2 diabetes) rats also contained OX1R.
Localization (pancreas) of GK in pancreas associated with diabetes mellitus
3) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2799220 Disease Relevance 0.75 Pain Relevance 0

General Comments

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