INT47983

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Context Info
Confidence 0.22
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.32
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TFPI) extracellular region (TFPI) plasma membrane (TFPI)
Anatomy Link Frequency
EPI 4
TFPI (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 91.44 High High
cINOD 1 64.68 Quite High
rheumatoid arthritis 1 49.12 Quite Low
Catecholamine 14 46.04 Quite Low
agonist 32 5.00 Very Low Very Low Very Low
antagonist 18 5.00 Very Low Very Low Very Low
Potency 8 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 91.44 High High
Disease 2 89.72 High High
Neuroblastoma 16 26.00 Quite Low
Aids-related Complex 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This propranolol concentration (30 nM) is sufficient to prevent EPI activation of ?
Negative_regulation (prevent) of Positive_regulation (activation) of EPI in EPI
1) Confidence 0.22 Published 2007 Journal BMC Pharmacol Section Body Doc Link PMC2234403 Disease Relevance 0 Pain Relevance 0
Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells.
Negative_regulation (inhibit) of Positive_regulation (activation) of tissue factor gene
2) Confidence 0.20 Published 1995 Journal Blood Section Title Doc Link 7492771 Disease Relevance 0.32 Pain Relevance 0.15
2A-AR desensitization and down-regulation also attenuated EPI-induced increase in GRK2 and GRK3 content in the membrane fraction (P < 0.05; Fig. 6).
Negative_regulation (attenuated) of Positive_regulation (increase) of EPI-induced in EPI
3) Confidence 0.16 Published 2007 Journal BMC Pharmacol Section Body Doc Link PMC2234403 Disease Relevance 0 Pain Relevance 0

General Comments

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