INT48064

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Context Info
Confidence 0.01
First Reported 1995
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.04
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

USHBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 2 99.98 Very High Very High Very High
COX-2 inhibitor 2 79.64 Quite High
cerebral cortex 1 77.20 Quite High
cytokine 14 62.72 Quite High
Enkephalin 2 25.00 Low Low
cINOD 2 19.56 Low Low
aspirin 1 17.64 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 24 92.40 High High
Cancer 81 90.92 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 141 62.52 Quite High
Malignant Neoplastic Disease 4 48.84 Quite Low
Apoptosis 9 47.16 Quite Low
Infection 11 39.92 Quite Low
Disease 9 27.84 Quite Low
INFLAMMATION 6 19.32 Low Low
Dementia 9 5.00 Very Low Very Low Very Low
Immunodeficiency 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent in vitro study demonstrated that wild type p53 inhibits the formation of the complex between TATA binding protein and the promoter region of COX-2 gene in a cell-free system (18).
binding protein Binding (formation) of
1) Confidence 0.01 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2721998 Disease Relevance 0.92 Pain Relevance 0.04
IR-receptor proteins have also been immunodetected using an antibody raised against an approximately 70-kD idazoxan/clonidine binding protein, which probably recognizes all types of IRs.
binding protein Binding (recognizes) of associated with clonidine
2) Confidence 0.00 Published 2003 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 15028606 Disease Relevance 0 Pain Relevance 0.23
The reduction of LTR expression is possibly explained by the binding of methyl-CpG-binding protein 1 complex and methyl-CpG-binding protein 2 to methylated Sp1 transcription factor binding sites, thereby inhibiting the binding of Sp1 transcription factors [282,283].
binding protein Binding (binding) of
3) Confidence 0.00 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.12 Pain Relevance 0.09
The CRE-binding protein (CREB) binds CRE-1, but binding there is entirely dependent on the presence of CRE-2.
CRE-binding protein Binding (binds) of
4) Confidence 0.00 Published 1995 Journal J. Biol. Chem. Section Abstract Doc Link 7499237 Disease Relevance 0 Pain Relevance 0

General Comments

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