INT48216

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Context Info
Confidence 0.58
First Reported 1994
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.89
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Mak)
Anatomy Link Frequency
male germ cell 2
Mak (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 8 72.40 Quite High
cytokine 14 71.20 Quite High
adenocard 6 66.80 Quite High
pain flank 1 65.40 Quite High
metalloproteinase 12 60.92 Quite High
Dismenorea 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Cancer 10 99.52 Very High Very High Very High
Cancer 4 98.34 Very High Very High Very High
Transitional Cell Carcinoma 9 92.80 High High
Malignant Neoplastic Disease 1 76.08 Quite High
Nicotine Addiction 1 73.84 Quite High
Bladder Cancer 1 71.76 Quite High
Metastasis 1 68.44 Quite High
Flank Pain 1 65.40 Quite High
Hematuria 1 64.68 Quite High
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
down regulated the expression of serum glucocorticoid kinase (SGK), casein kinase I, extracellular signal-regulated kinase (ERK-1), male germ cell-associated kinase (MAK), and Wee tyrosine kinase.
Gene_expression (expression) of MAK in male germ cell
1) Confidence 0.58 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC548144 Disease Relevance 0 Pain Relevance 0.14
down regulated the expression of serum glucocorticoid kinase (SGK), casein kinase I, extracellular signal-regulated kinase (ERK-1), male germ cell-associated kinase (MAK), and Wee tyrosine kinase.
Gene_expression (expression) of cell-associated kinase in male germ cell
2) Confidence 0.15 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC548144 Disease Relevance 0 Pain Relevance 0.14
The tumor tissue infiltrating the lymphatics, which seemed to be RCC, demonstrated positive staining for EMA and keratins CAM-5.2, AE1/AE3, and MAK-6 and negative staining for keratin 34 beta E12.
Gene_expression (staining) of MAK-6 associated with cancer and renal cancer
3) Confidence 0.01 Published 1994 Journal Cancer Section Abstract Doc Link 7506117 Disease Relevance 1.89 Pain Relevance 0.07

General Comments

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