INT48239
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Additionally, we assessed the effect of a monoclonal antibody that binds to and sequesters nerve growth factor (anti-NGF) on pain-related behaviors and bone healing (mechanical properties and histomorphometric analysis) after fracture. | |||||||||||||||
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Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. | |||||||||||||||
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CONCLUSIONS: Laparotomy is associated with higher levels of a heparin-binding plasma factor, consistent with PDGF. | |||||||||||||||
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It has recently become clear that the neurotrophic factor, nerve growth factor, interacts specifically with nociceptive sensory neurons during development and maturity. | |||||||||||||||
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The phosphorylation of ERK was reduced by tyrphostin AG1478, an inhibitor of phosphorylation of the epidermal growth factor receptor (EGFR), and by heparin, which neutralizes heparin-binding epithelial growth factor (HB-EGF), suggesting the involvement of a transactivation process, in which alpha(2)-adrenergic stimulation leads to proteolytic shedding of HB-EGF (and perhaps other EGFR agonists) from transmembrane-spanning precursors. | |||||||||||||||
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Sohn et al. showed that the ligation of a C3 complement activation factor (iC3b), which is constitutively present in aqueous humor, stimulates APC upregulation of IL-10 and TGF-? | |||||||||||||||
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The association between the risk factor and the disease may thus be easier to detect. | |||||||||||||||
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0.04) and refrigerator exposure at birth was found to be a risk factor for CD (OR? | |||||||||||||||
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Moreover, G-CSF is a pleiotropic factor that for example also impacts on immunocompetence and inflammatory reactions. | |||||||||||||||
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The potential for IL-9 to be a mast cell growth factor has been recognized in studies of IL-9 transgenic mice which have significantly increased levels of mast cells in various tissues including the lung (Godfraind et al. 2009; Temann et al. 1988). | |||||||||||||||
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Administration of the neurotrophin nerve growth factor (NGF) to rats and humans has been shown to induce both thermal and mechanical hyperalgesia and is used as a model of inflammatory pain. | |||||||||||||||
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Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family of growth factors that includes EGF, transforming growth factor (TGF)-? | |||||||||||||||
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Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family, serves as a neurotrophic molecular and plays a significant role in the brain. | |||||||||||||||
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Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family, serves as a neurotrophic molecular and plays a significant role in the brain. | |||||||||||||||
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Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family of growth factors that includes EGF, transforming growth factor (TGF)-? | |||||||||||||||
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The polymorphism -260 T>C [dbSNP: rs2569190] has been shown to increase transcriptional activity by lowering the affinity of the GC box for Sp3, a factor known to inhibit the activity of a number of promoters. | |||||||||||||||
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A compatibility study showed that hTF can bind to murine Factor VIIa with high affinity to induce coagulation [35], while mTF binds poorly to human Factor VIIa [35], [36]. | |||||||||||||||
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Circulating tumour necrosis factor-? | |||||||||||||||
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A further example of the newly identified mouse liver protein is the hepatoma-derived growth factor (Swiss-Prot: P51859), e.g. a heparin-binding protein with mitogenic activity in fibroblasts. | |||||||||||||||
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A wide range of molecular function gene ontology terms were overrepresented, the most significant of which were monooxygenase activity, heme binding, iron ion binding and insulin-like growth factor binding (P < 0.01). | |||||||||||||||
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General Comments
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