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Context Info
Confidence 0.16
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.29
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CSF2) extracellular region (CSF2) cell adhesion (ITGAM)
plasma membrane (ITGAM)
Anatomy Link Frequency
granulocyte 2
neutrophils 2
CSF2 (Homo sapiens)
ITGAM (Homo sapiens)
Pain Link Frequency Relevance Heat
local anesthetic 2 86.24 High High
lidocaine 7 84.88 Quite High
analgesia 1 82.60 Quite High
Inflammation 2 34.88 Quite Low
cytokine 1 29.68 Quite Low
Regional anesthesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Adhesions 5 100.00 Very High Very High Very High
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We further studied the effects of Lido on the priming of canine granulocyte CD11b expression and ROS production by recombinant canine granulocyte macrophage colony stimulating factor (rcGM-CSF).
rcGM-CSF Regulation (effects) of Gene_expression (expression) of CD11b in granulocyte
1) Confidence 0.16 Published 2010 Journal J. Vet. Med. Sci. Section Abstract Doc Link 19940395 Disease Relevance 0.09 Pain Relevance 0.24
Recombinant human granulocyte colony-stimulating factor (rhG-CSF) enhanced superoxide (O2-) release in human neutrophils stimulated by the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) and inversely regulated the surface expression of cellular adhesion molecules, leukocyte adhesion molecule-1 (LAM-1) and CD11b/CD18 leukocyte integrin, on human neutrophils; that is, rhG-CSF downregulated the expression of LAM-1 and upregulated the expression of CD11b on neutrophils.
rhG-CSF Regulation (regulated) of Gene_expression (expression) of CD11b in neutrophils associated with adhesions
2) Confidence 0.15 Published 1994 Journal Exp. Hematol. Section Abstract Doc Link 7513653 Disease Relevance 0.20 Pain Relevance 0.44

General Comments

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