INT48445

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Context Info
Confidence 0.11
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.14
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il3) extracellular region (Il3)
Anatomy Link Frequency
granulocyte 1
blood 1
adrenal gland 1
Il3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tolerance 2 99.38 Very High Very High Very High
cytokine 9 91.52 High High
medulla 8 79.40 Quite High
antagonist 2 64.96 Quite High
COX-2 inhibitor 1 64.56 Quite High
Catecholamine 1 63.68 Quite High
anesthesia 1 60.08 Quite High
cINOD 8 57.68 Quite High
Inflammation 16 50.00 Quite Low
Clonidine 2 46.00 Quite Low
Disease Link Frequency Relevance Heat
Toxicity 7 90.80 High High
Fever 2 53.04 Quite High
INFLAMMATION 21 50.00 Quite Low
Arthralgia 1 47.60 Quite Low
Headache 1 44.48 Quite Low
Vomiting 4 41.60 Quite Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Gallstones 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since interleukins can also activate the hypothalamus-hypophysis-adrenal gland axis (Weber et al. 1997) there were examined the effects of action of human recombined IL-3 and IL-6 on cortisol secretion by the cells of human adrenal cortex in primary culture.
Localization (secretion) of IL-3 in adrenal gland
1) Confidence 0.11 Published 2010 Journal Protoplasma Section Body Doc Link PMC2947012 Disease Relevance 0 Pain Relevance 0.20
A pilot study was devised to assess tolerance of combined administration of interleukin-3 (IL-3) and granulocyte-colony stimulating factor (G-CSF) given after chemotherapy to mobilize peripheral blood progenitors cells (PBPC).
Localization (mobilize) of interleukin-3 in blood associated with tolerance
2) Confidence 0.03 Published 1994 Journal Bone Marrow Transplant. Section Abstract Doc Link 7515299 Disease Relevance 0.05 Pain Relevance 0.12
Thirty-five consecutive patients were non-random sequentially allocated to one of three treatment groups: (1) granulocyte colony-stimulating factor alone (n = 15); (2) granulocyte-macrophage colony-stimulating factor alone (n = 10), and (3) sequential interleukin-3 and granulocyte-macrophage colony-stimulating factor (n = 10).
Localization (allocated) of interleukin-3 in granulocyte
3) Confidence 0.03 Published 2000 Journal Oncology Section Abstract Doc Link 10895059 Disease Relevance 0.09 Pain Relevance 0.17

General Comments

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