INT48526

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Context Info
Confidence 0.24
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.03
Pain Relevance 2.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Calca, Penk) extracellular space (Calca) aging (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
spinal cord 2
Calca (Rattus norvegicus)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 16 100.00 Very High Very High Very High
Enkephalin 12 100.00 Very High Very High Very High
Calcitonin gene-related peptide 12 100.00 Very High Very High Very High
Neuropeptide 4 99.76 Very High Very High Very High
Pain 4 99.30 Very High Very High Very High
Spinal cord 8 98.32 Very High Very High Very High
Dorsal horn 12 97.94 Very High Very High Very High
Inflammation 4 86.16 High High
Hyperalgesia 4 84.80 Quite High
mu opioid receptor 2 68.80 Quite High
Disease Link Frequency Relevance Heat
Pain 4 99.30 Very High Very High Very High
Arthritis 10 90.56 High High
INFLAMMATION 4 86.16 High High
Hyperalgesia 4 84.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The dorsal horn of the spinal cord, which forms the locus of first synapses in pain pathways, is an important site of interaction between calcitonin gene-related peptide (CGRP), substance P and enkephalin--the neuropeptides considered to be especially involved in the regulation of pain perception.
calcitonin gene-related peptide Binding (interaction) of enkephalin in spinal cord associated with pain, neuropeptide, dorsal horn, enkephalin, substance p, calcitonin gene-related peptide and spinal cord
1) Confidence 0.24 Published 1994 Journal Eur. J. Neurosci. Section Abstract Doc Link 7517279 Disease Relevance 0.52 Pain Relevance 1.26
The dorsal horn of the spinal cord, which forms the locus of first synapses in pain pathways, is an important site of interaction between calcitonin gene-related peptide (CGRP), substance P and enkephalin--the neuropeptides considered to be especially involved in the regulation of pain perception.
CGRP Binding (interaction) of enkephalin in spinal cord associated with pain, neuropeptide, dorsal horn, enkephalin, substance p, calcitonin gene-related peptide and spinal cord
2) Confidence 0.24 Published 1994 Journal Eur. J. Neurosci. Section Abstract Doc Link 7517279 Disease Relevance 0.52 Pain Relevance 1.26

General Comments

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