INT48592

Context Info Confidence 0.40 First Reported 1994 Last Reported 1994 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0.66

peptidase activity (MME) plasma membrane (MME) cell-cell signaling (MME)

Anatomy Link Frequency granulocytes 2 MME (Homo sapiens)

Pain Link Frequency Relevance Heat Neuropeptide 1 99.98 Morphine 4 96.56 narcan 2 94.32 substance P 4 86.16 cytokine 1 58.32 opiate 1 53.52

Disease Link Frequency Relevance Heat Necrosis 2 83.88 Cancer 2 83.52

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We have previously shown that neutral endopeptidase 24.11 (NEP) is an important enzyme in neuro- and autoimmunoregulation of both vertebrates and invertebrates, and that activation of human granulocytes by monokines and neuropeptides results in regulation of NEP.

Positive_regulation (results) of Regulation (regulation) of NEP in granulocytes associated with neuropeptide

1) Confidence 0.40 Published 1994 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 7519178 Disease Relevance 0.32 Pain Relevance 0.66

General Comments

This test has worked.