INT48636

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Context Info
Confidence 0.42
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 7.14
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Pts) lyase activity (Pts) cellular_component (Pts)
cytoplasm (Pts)
Anatomy Link Frequency
blood 1
spinal 1
Pts (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 6 92.24 High High
Pain 15 85.76 High High
Migraine 3 80.60 Quite High
headache 2 77.84 Quite High
imagery 1 75.96 Quite High
Transcranial magnetic stimulation 2 75.12 Quite High
Multiple sclerosis 2 75.00 Quite High
Lasting pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 14 100.00 Very High Very High Very High
Postthrombotic Syndrome 12 100.00 Very High Very High Very High
Muscular Spasm 5 100.00 Very High Very High Very High
Epilepsy 10 99.84 Very High Very High Very High
Hemoglobinuria 2 99.20 Very High Very High Very High
Hemorrhage 2 98.16 Very High Very High Very High
Anaemia 6 97.32 Very High Very High Very High
Cancer 2 95.08 Very High Very High Very High
Thrombosis 17 95.04 Very High Very High Very High
Sickle Cell Anemia 4 94.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patients were screened for PTS using Kuhle's PTS pediatric score.
Positive_regulation (screened) of PTS
1) Confidence 0.42 Published 2010 Journal Pediatr Blood Cancer Section Body Doc Link 20232430 Disease Relevance 0.19 Pain Relevance 0
In turn, preservation of the underlying pyramidal-spinal tract could make it easier for the pathologic discharge to reach the peripheral effectors and generate PTS.
Positive_regulation (generate) of PTS in spinal associated with muscular spasm
2) Confidence 0.39 Published 1999 Journal Mov. Disord. Section Abstract Doc Link 10091629 Disease Relevance 0.63 Pain Relevance 0.25
Generally, PTs had higher variance in migraineurs than in controls, revealing a significant increase in standard deviation of PTs in MA subjects.
Positive_regulation (increase) of PTs associated with epilepsy
3) Confidence 0.35 Published 2006 Journal Cephalalgia Section Abstract Doc Link 16776703 Disease Relevance 1.19 Pain Relevance 0.38
Increasing the awareness of PTS, and the methods to prevent this complication may help reduce its incidence, improve long-term outcomes in patients, and decrease resulting costs associated with treatment.
Positive_regulation (Increasing) of PTS associated with syndrome
4) Confidence 0.32 Published 2009 Journal J. Thromb. Thrombolysis Section Abstract Doc Link 19224134 Disease Relevance 1.76 Pain Relevance 0.07
Certain risk factors predispose children to PTS including elevations in factor VIII activity and D-dimer, clot occlusiveness, clot persistence, number of venous segments involved and duration of observation following DVT.
Positive_regulation (elevations) of PTS associated with postthrombotic syndrome and thrombosis
5) Confidence 0.28 Published 2006 Journal Acta Haematol. Section Abstract Doc Link 16549898 Disease Relevance 1.06 Pain Relevance 0.11
PTS is caused by both obstructed as well as refluxed venous blood flow, with combined effects of obstruction and reflux resulting in earlier, and more extensive symptoms.
Positive_regulation (caused) of PTS in blood associated with postthrombotic syndrome
6) Confidence 0.28 Published 2006 Journal Acta Haematol. Section Abstract Doc Link 16549898 Disease Relevance 1.11 Pain Relevance 0.13
In one of the Pts. the 51Cr RBC T1/2 survival increased from 12 to 16 days.
Positive_regulation (increased) of Pts
7) Confidence 0.19 Published 1994 Journal Am. J. Hematol. Section Abstract Doc Link 7522396 Disease Relevance 0.60 Pain Relevance 0.06
In the other two Pts. iron restriction was induced by periodic RBC aphereses as part of a pilot protocol designed to decrease intracellular HbS polymerization by MCHC reduction.
Positive_regulation (induced) of Pts
8) Confidence 0.19 Published 1994 Journal Am. J. Hematol. Section Abstract Doc Link 7522396 Disease Relevance 0.60 Pain Relevance 0

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