INT48643

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Context Info
Confidence 0.53
First Reported 1993
Last Reported 2009
Negated 2
Speculated 2
Reported most in Abstract
Documents 6
Total Number 8
Disease Relevance 1.94
Pain Relevance 3.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TCEA1) nucleolus (TCEA1) nucleus (TCEA1)
DNA binding (TCEA1)
Anatomy Link Frequency
neurons 6
nucleus 4
cerebral cortex 2
SII 2
TCEA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatosensory cortex 9 100.00 Very High Very High Very High
primary somatosensory cortex 5 100.00 Very High Very High Very High
electroacupuncture 16 99.84 Very High Very High Very High
analgesia 4 99.46 Very High Very High Very High
Acupuncture 4 99.26 Very High Very High Very High
Trigeminal neuralgia 9 99.00 Very High Very High Very High
nociceptor 3 98.94 Very High Very High Very High
Pain 14 98.76 Very High Very High Very High
substance P 8 98.76 Very High Very High Very High
Thalamus 6 98.58 Very High Very High Very High
Disease Link Frequency Relevance Heat
Nociception 9 100.00 Very High Very High Very High
Headache 9 99.00 Very High Very High Very High
Pain 6 95.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that SI and SII activations in patients did neither depend on the affected side of TN nor differ between operated and nonoperated patients.
Neg (nor) Regulation (depend) of Positive_regulation (activations) of SII associated with trigeminal neuralgia
1) Confidence 0.53 Published 2009 Journal Hum Brain Mapp Section Abstract Doc Link 19365802 Disease Relevance 1.15 Pain Relevance 1.27
[Influence of cooling motor cortex on the inhibitory effect of stimulation of SII on nociceptive responses in ILN neurons].
Regulation (effect) of Positive_regulation (stimulation) of SII in neurons associated with nociception and nociceptor
2) Confidence 0.33 Published 1994 Journal Zhen Ci Yan Jiu Section Title Doc Link 7750169 Disease Relevance 0.25 Pain Relevance 0.10
In this fMRI study we investigated the effect of attention on the activation of SI and SII, as induced by nonpainful and painful rare deviant electric stimuli during somatosensory oddball tasks.
Spec (investigated) Regulation (effect) of Spec (investigated) Positive_regulation (activation) of SII in SII associated with pain, somatosensory cortex and primary somatosensory cortex
3) Confidence 0.23 Published 2008 Journal Neuroimage Section Abstract Doc Link 18329293 Disease Relevance 0 Pain Relevance 0.68
The effects of stimulating SII on nociceptive responses of ILN neurons were observed before and after cooling MCtx.
Regulation (responses) of Positive_regulation (stimulating) of SII in neurons associated with nociception
4) Confidence 0.20 Published 1994 Journal Zhen Ci Yan Jiu Section Abstract Doc Link 7750169 Disease Relevance 0.27 Pain Relevance 0
The effects of stimulating SII on nociceptive responses of ILN neurons were observed before and after cooling MCtx.
Regulation (effects) of Positive_regulation (stimulating) of SII in neurons associated with nociception
5) Confidence 0.20 Published 1994 Journal Zhen Ci Yan Jiu Section Abstract Doc Link 7750169 Disease Relevance 0.27 Pain Relevance 0
[Effects of electrical stimulation of SII and electroacupuncture on beta-endorphin contents in the perfusate from the nucleus centrum medianum of the thalamus in cats].
Regulation (Effects) of Positive_regulation (stimulation) of SII in nucleus associated with thalamus and electroacupuncture
6) Confidence 0.10 Published 1996 Journal Zhen Ci Yan Jiu Section Title Doc Link 9388314 Disease Relevance 0 Pain Relevance 0.45
In order to probe into whether beta-endorphin is involved in descending modulation of the somatosensory area (SII) of the cerebral cortex on the nucleus centrum medianum (CM) of the thalamus and this mechanism of acupuncture analgesia, it was investigated that effects of electrical stimulation of SII and electroacupuncture on beta-endorphin content in the perfusate from the nucleus CM.
Spec (investigated) Regulation (effects) of Spec (investigated) Positive_regulation (stimulation) of SII in cerebral cortex associated with acupuncture, thalamus, electroacupuncture, cerebral cortex and analgesia
7) Confidence 0.10 Published 1996 Journal Zhen Ci Yan Jiu Section Abstract Doc Link 9388314 Disease Relevance 0 Pain Relevance 0.45
The results showed that SP contents in the perfusate have not statistically significant changes before and after the electrical stimulation of SII or electroacupuncture, suggesting that the SP release from the nucleus CM was not influenced by the stimulation of SII or electroacupuncture.
Neg (not) Regulation (changes) of Positive_regulation (stimulation) of SII in nucleus associated with electroacupuncture and substance p
8) Confidence 0.04 Published 1993 Journal Zhen Ci Yan Jiu Section Abstract Doc Link 7522994 Disease Relevance 0 Pain Relevance 0.89

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