INT48944

Context Info Confidence 0.41 First Reported 1994 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 8 Total Number 8 Disease Relevance 3.23 Pain Relevance 1.03

mitochondrion (Pts) lyase activity (Pts) cellular_component (Pts) cytoplasm (Pts)

Anatomy Link Frequency spinal cord 1 brain 1 Pts (Rattus norvegicus)

Pain Link Frequency Relevance Heat Tetrahydrobiopterin 8 100.00 Spinal cord 3 100.00 Arachnoiditis 1 99.76 Neurotransmitter 1 96.24 Dopamine 1 95.52 anesthesia 1 95.00 Serotonin 1 95.00 Pain 7 92.48 Antinociceptive 1 75.00 syringomyelia 1 75.00

Disease Link Frequency Relevance Heat Syndrome 18 100.00 Obesity 9 100.00 Injury 8 100.00 Spinal Cord Injury 2 100.00 Arachnoiditis 1 99.76 Thrombosis 7 98.88 Pain 6 92.48 Syringomyelia 1 75.00 Overweight 1 65.52 Cancer 2 62.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PTS follows complete spinal cord injury (SCI) more often than incomplete and is frequently associated with arachnoiditis.

PTS Binding (associated) of in spinal cord associated with arachnoiditis, injury and spinal cord

1) Confidence 0.41 Published 2002 Journal Br J Neurosurg Section Abstract Doc Link 12201398 Disease Relevance 1.13 Pain Relevance 0.26

PTPS is a biosynthetic enzyme for the BH4 co-factor, and its deficiency is associated with a malfunction of the phenylalanine catabolism in the liver and a lack of biogenic amine neurotransmitters dopamine and serotonin in the brain.

PTPS Binding (associated) of in brain associated with dopamine, neurotransmitter, tetrahydrobiopterin and serotonin

2) Confidence 0.33 Published 1996 Journal Hum. Gene Ther. Section Abstract Doc Link 8864759 Disease Relevance 0 Pain Relevance 0.51

CONCLUSIONS: Screening cancer survivors for PTS after CVC removal should be integrated to the after cancer follow-up clinic.

PTS Binding (integrated) of

3) Confidence 0.31 Published 2010 Journal Pediatr Blood Cancer Section Body Doc Link 20232430 Disease Relevance 0.12 Pain Relevance 0

The aim of this study was to assess the association between BMI and other anthropometric parameters and PTS in a general population of DVT patients.

PTS Binding (association) of associated with syndrome, obesity and thrombosis

4) Confidence 0.30 Published 2003 Journal Thromb. Haemost. Section Abstract Doc Link 12574811 Disease Relevance 1.79 Pain Relevance 0

All these factors have to be considered to improve the interaction between PTs and persons who have undergone torture.

PTs Binding (interaction) of

5) Confidence 0.14 Published 2007 Journal Physiother Theory Pract Section Abstract Doc Link 17454798 Disease Relevance 0 Pain Relevance 0

The aim of this study was to identify factors important for a good interaction between physiotherapist (PT) and the patient among PTs specialising in refugees who have been tortured.

PTs Binding (interaction) of

6) Confidence 0.12 Published 2007 Journal Physiother Theory Pract Section Abstract Doc Link 17454798 Disease Relevance 0.18 Pain Relevance 0.18

The next step is for clinical nurses, OTs and PTs to link with their local university and establish collaborations for enhancing rheumatology teaching in ways that best suit local needs and resources.

PTs Binding (link) of

7) Confidence 0.01 Published 2008 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2430217 Disease Relevance 0 Pain Relevance 0

Finally, binding of radiolabelled tetrahydrobiopterin, a NOS cofactor with unknown function, was also antagonized by 7-NI with a KI of 0.12 +/- 0.023 microM.

tetrahydrobiopterin Binding (binding) of associated with tetrahydrobiopterin

8) Confidence 0.00 Published 1994 Journal Neuropharmacology Section Abstract Doc Link 7532811 Disease Relevance 0 Pain Relevance 0.09

General Comments

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