INT48982

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Context Info
Confidence 0.45
First Reported 1995
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (FOS) aging (FOS) nucleolus (FOS)
nucleus (FOS)
FOS (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 8 99.84 Very High Very High Very High
Limbic system 1 98.40 Very High Very High Very High
tetrodotoxin 2 95.60 Very High Very High Very High
Thalamus 2 92.84 High High
Opioid 1 65.88 Quite High
depression 1 57.08 Quite High
analgesia 1 56.04 Quite High
tolerance 1 54.12 Quite High
Calcium channel 1 41.44 Quite Low
Disease Link Frequency Relevance Heat
Stress 1 95.44 Very High Very High Very High
Respiratory Failure 1 57.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lindane (gamma-hexachlorocyclohexane), Bay K 8644, pentylenetetrazole, and picrotoxinin produced a significant increase in c-fos immunoreactivity and in c-fos mRNA expression.
Positive_regulation (increase) of Regulation (immunoreactivity) of c-fos
1) Confidence 0.45 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7534335 Disease Relevance 0 Pain Relevance 0.19
The c-fos response was inducible by morphine in pretreated animals for up to 8 weeks after finishing the repeated application scheme.
Positive_regulation (inducible) of Regulation (response) of c-fos associated with morphine
2) Confidence 0.45 Published 1999 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 10521594 Disease Relevance 0.15 Pain Relevance 0.92

General Comments

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