INT4928

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Context Info
Confidence 0.26
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 7.62
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Mag)
Anatomy Link Frequency
neurons 2
B cells 2
peripheral nerves 1
bone marrow 1
neurite 1
Mag (Rattus norvegicus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 2 99.72 Very High Very High Very High
Multiple sclerosis 13 99.24 Very High Very High Very High
Peripheral nervous system 5 92.56 High High
Neuritis 3 88.56 High High
Inflammation 8 87.36 High High
Pain 4 83.92 Quite High
antagonist 1 83.08 Quite High
headache 1 72.88 Quite High
Spinal cord 21 71.36 Quite High
Central nervous system 11 19.36 Low Low
Disease Link Frequency Relevance Heat
Peripheral Neuropathy 2 99.72 Very High Very High Very High
Demyelinating Disease 21 99.28 Very High Very High Very High
Neuropathy 12 98.74 Very High Very High Very High
Pancreatic Cancer 16 98.60 Very High Very High Very High
Charcot Marie Tooth Disease 7 97.88 Very High Very High Very High
Neuropathic Pain 3 96.88 Very High Very High Very High
Adhesions 17 93.44 High High
Neuritis 1 88.56 High High
Optic Neuritis 2 88.20 High High
INFLAMMATION 9 87.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results support the hypothesis that the adhesive interactions between MUC1 and MAG are of biological significance in pancreatic cancer perineural invasion.
MAG Binding (interactions) of associated with pancreatic cancer
1) Confidence 0.26 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.66 Pain Relevance 0
Results showed that MAG binds pancreatic cells expressing MUC1, that this binding is sialidase-sensitive, and that MAG physically associates with MUC1.
MAG Binding (binds) of
2) Confidence 0.26 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.90 Pain Relevance 0.07
Myelin-associated glycoprotein (MAG), a membrane-bound protein expressed on oligodendrocytes and Schwann cells, binds myelin to neurons.
Myelin-associated glycoprotein Binding (binds) of in neurons
3) Confidence 0.26 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.90 Pain Relevance 0.08
Myelin-associated glycoprotein (MAG), a membrane-bound protein expressed on oligodendrocytes and Schwann cells, binds myelin to neurons.
MAG Binding (binds) of in neurons
4) Confidence 0.26 Published 2007 Journal Cancer Res. Section Abstract Doc Link 17974963 Disease Relevance 0.89 Pain Relevance 0.08
Multiple MAG peptides are recognized by circulating T and B lymphocytes in polyneuropathy and multiple sclerosis.
MAG Binding (recognized) of in B lymphocytes associated with neuropathy and multiple sclerosis
5) Confidence 0.25 Published 2002 Journal Eur. J. Neurol. Section Title Doc Link 11985632 Disease Relevance 1.05 Pain Relevance 0.41
Patients with polyneuropathy as well as those with MS had elevated levels of T and B cells recognizing MAG and its peptides.
MAG Binding (recognizing) of in B cells associated with neuropathy and multiple sclerosis
6) Confidence 0.25 Published 2002 Journal Eur. J. Neurol. Section Abstract Doc Link 11985632 Disease Relevance 1.16 Pain Relevance 0.41
In three of them, including two siblings with a demyelinating peripheral neuropathy, the IgM was bound to the myelin-associated glycoprotein (MAG) of peripheral nerves.
MAG Binding (bound) of in peripheral nerves associated with peripheral neuropathy and demyelinating disease
7) Confidence 0.09 Published 1988 Journal Acta Med Scand Section Abstract Doc Link 3354352 Disease Relevance 0.71 Pain Relevance 0.18
This inhibition of MAG binding to NgR suppressed the signalling by NgR and allowed neurite regeneration to take place.
MAG Binding (binding) of in neurite
8) Confidence 0.08 Published 2010 Journal Surgical Neurology International Section Body Doc Link PMC3019362 Disease Relevance 0.37 Pain Relevance 0.11
Patients with both HMSN I and the other polyneuropathies had few cells in peripheral blood and in bone marrow producing antibodies binding to P2, MAG and MBP in a solid phase immunospot assay.
MAG Binding (binding) of in bone marrow associated with neuropathy and charcot marie tooth disease
9) Confidence 0.07 Published 1992 Journal J. Neurol. Sci. Section Abstract Doc Link 1281871 Disease Relevance 0.98 Pain Relevance 0.07

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