INT49325

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 1995
Last Reported 2011
Negated 29
Speculated 2
Reported most in Abstract
Documents 102
Total Number 104
Disease Relevance 82.75
Pain Relevance 8.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cd34) extracellular region (Cd34) cell motility (Cd34)
cell adhesion (Cd34) plasma membrane (Cd34) transcription factor binding (Cd34)
Anatomy Link Frequency
smooth muscle 11
B cell 4
interstitial cells 3
bone marrow 3
stem cell 3
Cd34 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 10 100.00 Very High Very High Very High
Inflammation 99 99.58 Very High Very High Very High
chemokine 9 98.32 Very High Very High Very High
Angina 4 97.68 Very High Very High Very High
Dismenorea 9 97.32 Very High Very High Very High
ischemia 39 96.36 Very High Very High Very High
endometriosis 8 96.28 Very High Very High Very High
Pain 47 94.28 High High
palliative 10 94.00 High High
headache 12 92.36 High High
Disease Link Frequency Relevance Heat
Microphthalmia 1 100.00 Very High Very High Very High
Multiple System Atrophy 1 100.00 Very High Very High Very High
Cancer 686 99.98 Very High Very High Very High
Skin Cancer 52 99.90 Very High Very High Very High
Chromosome Aberrations 4 99.90 Very High Very High Very High
Polyps 13 99.88 Very High Very High Very High
Synovial Sarcoma 20 99.84 Very High Very High Very High
Ganglion Cysts 5 99.76 Very High Very High Very High
Gastrointestinal Stromal Tumor 51 99.74 Very High Very High Very High
Uterine Fibroids 23 99.74 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In approximately 30 minutes, 450 milliliters of marrow can be collected from eight bone punctures, containing a median of 4.18 x 10(9) cells and 33 x 10(6) progenitor cells as defined by CD34 expression.
Gene_expression (expression) of CD34 in punctures
1) Confidence 0.78 Published 1995 Journal Exp. Hematol. Section Abstract Doc Link 7556535 Disease Relevance 0.19 Pain Relevance 0.16
In patients that received potential curative therapies LDH >or=2000 U/l, WBC >50 GPT/l, CD34 surface expression on the AML blasts, secondary AML, unfavorable karyotype and no allogeneic HSCT at some point of treatment course were associated with unfavorable prognosis.
Gene_expression (expression) of CD34 associated with myeloid leukemia
2) Confidence 0.77 Published 2005 Journal Neoplasma Section Abstract Doc Link 16151585 Disease Relevance 0.81 Pain Relevance 0.09
Multivariate analyses of prognostic factors in acute myeloid leukemia: relevance of cytogenetic abnormalities and CD34 expression.
Gene_expression (expression) of CD34 associated with chromosome aberrations and leukemia
3) Confidence 0.77 Published 2005 Journal Neoplasma Section Title Doc Link 16151585 Disease Relevance 0.82 Pain Relevance 0.07
In conclusion, karyotype and CD34 expression are independent prognostic markers in newly diagnosed AML.
Gene_expression (expression) of CD34 associated with myeloid leukemia
4) Confidence 0.77 Published 2005 Journal Neoplasma Section Abstract Doc Link 16151585 Disease Relevance 0.80 Pain Relevance 0.08
Unfortunately, virtually all patients will eventually relapse following autologous stem cell transplantation, prompting continuing efforts such as tandem transplants, CD34+ selection, as well as modifications in the conditioning regimen to improve outcomes.
Gene_expression (selection) of CD34 in stem cell associated with recurrence
5) Confidence 0.67 Published 2003 Journal Drugs Section Abstract Doc Link 12904084 Disease Relevance 0.44 Pain Relevance 0.05
Dual-stained cells expressing CD34 and vascular endothelial growth factor receptor-2 were judged to be endothelial progenitor cells and were analyzed using flow cytometry.
Gene_expression (expressing) of CD34
6) Confidence 0.62 Published 2008 Journal Heart Vessels Section Abstract Doc Link 18273546 Disease Relevance 0.60 Pain Relevance 0.10
Here, we could demonstrate that this accumulation was not selective for CD34+.
Neg (not) Gene_expression (selective) of CD34
7) Confidence 0.61 Published 2005 Journal GMS German Medical Science Section Body Doc Link PMC2703252 Disease Relevance 0.36 Pain Relevance 0
Again, after administration of CD34+ as well as CD34- cells, CFSE labelled cells were found that accumulated in the border zone between the central necrosis of the ischemic lesion and functional brain tissue, thus indicating active attraction towards the lesion for both cell populations.
Gene_expression (administration) of CD34 in brain associated with necrosis
8) Confidence 0.61 Published 2005 Journal GMS German Medical Science Section Abstract Doc Link PMC2703252 Disease Relevance 0.86 Pain Relevance 0
The enrichment or depletion of CD34+ cells was performed using microbead-conjugated anti-CD34 antibodies (CD34 Progenitor Cell Isolation Kit), LS+/VS+ columns and a SuperMACS magnetic cell separator (all Miltenyi-Biotech Inc., Bergisch Gladbach, Germany) according to manufacturers instructions.
Gene_expression (antibodies) of CD34
9) Confidence 0.61 Published 2005 Journal GMS German Medical Science Section Body Doc Link PMC2703252 Disease Relevance 0 Pain Relevance 0
The enrichment or depletion of CD34+ cells was performed using microbead-conjugated anti-CD34 antibodies (CD34 Progenitor Cell Isolation Kit), LS+/VS+ columns and a SuperMACS magnetic cell separator (all Miltenyi-Biotech Inc., Bergisch Gladbach, Germany) according to manufacturers instructions.
Gene_expression (antibodies) of CD34
10) Confidence 0.61 Published 2005 Journal GMS German Medical Science Section Body Doc Link PMC2703252 Disease Relevance 0 Pain Relevance 0
Again, after administration of CD34+ as well as CD34- cells, CFSE labelled cells were found that accumulated in the border zone between the central necrosis of the ischemic lesion and functional brain tissue, thus indicating active attraction towards the lesion for both cell populations.
Gene_expression (administration) of CD34 in brain associated with necrosis
11) Confidence 0.61 Published 2005 Journal GMS German Medical Science Section Abstract Doc Link PMC2703252 Disease Relevance 0.86 Pain Relevance 0
Comparing CD34+ HUCB cells with CD34- HUCB cells, no statistically significant difference (P<0.05) was observed with regard to the beneficial effect of both populations (Figure 2A-D (Fig. 2)).
Gene_expression (Comparing) of CD34
12) Confidence 0.61 Published 2005 Journal GMS German Medical Science Section Body Doc Link PMC2703252 Disease Relevance 0 Pain Relevance 0
The number of BMMNCs expressing the CD34 surface marker and the viability of pooled cells were assessed by flow-cytometry analysis of 100,000 events per sample (FACScan, Becton Dickinson, Franklin Lakes, NJ).
Gene_expression (expressing) of CD34
13) Confidence 0.58 Published 2008 Journal J Transl Med Section Body Doc Link PMC2435101 Disease Relevance 0.14 Pain Relevance 0.03
A study on 62 cases of rectovaginal septum endometriosis by means of immunohistochemistry was conducted in order to evaluate the oestrogen and progesterone receptor levels in these cases and to correlate them to the level of vascularization (CD34 expression) and the amount of nerve fibres (S100 expression).
Gene_expression (expression) of CD34 in nerve associated with endometriosis
14) Confidence 0.58 Published 2009 Journal In Vivo Section Abstract Doc Link 19454514 Disease Relevance 0.43 Pain Relevance 0.26
Similar to the percentage observed in bone marrow, 1%-2% of mononuclear HUCB cells express CD34, the surface marker molecule of hemopoietic stem cells [2].
Gene_expression (express) of CD34 in bone marrow
15) Confidence 0.54 Published 2005 Journal GMS German Medical Science Section Body Doc Link PMC2703252 Disease Relevance 0.69 Pain Relevance 0.03
Comparing CD34+ HUCB cells with CD34- HUCB cells, no statistically significant difference (P<0.05) was observed with regard to the beneficial effect of both populations (Figure 2A-D (Fig. 2)).
Gene_expression (Comparing) of CD34
16) Confidence 0.53 Published 2005 Journal GMS German Medical Science Section Body Doc Link PMC2703252 Disease Relevance 0 Pain Relevance 0
The number of CD34+/CD45?
Gene_expression (/) of CD34
17) Confidence 0.51 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682571 Disease Relevance 0 Pain Relevance 0
The number of CD34+/CD45?
Gene_expression (number) of CD34
18) Confidence 0.51 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682571 Disease Relevance 0 Pain Relevance 0
Immunohistochemical staining was negative for the endothelial markers (CD31, CD34, and factor VIII-related antigen) and positive using cytokeratin antibodies (AE1/AE3 and 34 betaE12).
Neg (negative) Gene_expression (negative) of CD34
19) Confidence 0.51 Published 2005 Journal Am J Dermatopathol Section Abstract Doc Link 15798440 Disease Relevance 0.78 Pain Relevance 0.09
Most (82%) inflammatory fibroid polyps were positive for CD34 versus none of the inflammatory myofibroblastic tumors.
Neg (none) Gene_expression (positive) of CD34 associated with uterine fibroids, inflammation, cancer and polyps
20) Confidence 0.51 Published 2002 Journal Hum. Pathol. Section Abstract Doc Link 11979371 Disease Relevance 5.11 Pain Relevance 1.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox