INT49432

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 1995
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 0.27
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PTPRM) cell adhesion (PTPRM) cytoplasm (PTPRM)
Anatomy Link Frequency
embryonic kidney 3
neurons 1
PTPRM (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 11 100.00 Very High Very High Very High
analgesia 3 97.76 Very High Very High Very High
Pain 12 97.40 Very High Very High Very High
orphanin 3 93.24 High High
agonist 10 82.80 Quite High
Potency 6 75.00 Quite High
mu opioid receptor 3 75.00 Quite High
Morphine 3 68.64 Quite High
Enkephalin 4 65.60 Quite High
Disease Link Frequency Relevance Heat
Pain 3 97.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ORL1 and mu-opioid receptor (muR) are co-expressed in several subpopulations of CNS neurons involved in regulating pain transmission.
Gene_expression (co-expressed) of muR in neurons associated with pain and opioid receptor
1) Confidence 0.04 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 15748148 Disease Relevance 0.10 Pain Relevance 0.49
To test this hypothesis, myc-tagged ORL1 and HA-tagged muR are co-expressed in human embryonic kidney (HEK) 293 cells.
Gene_expression (co-expressed) of muR in embryonic kidney
2) Confidence 0.04 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 15748148 Disease Relevance 0.09 Pain Relevance 0.53
We expressed the cloned mu-opioid receptor (muR) in high abundance (5.5 x 10(6) sites/cell) with an amino-terminal epitope tag (EYMPME) in human embryonic kidney 293 cells.
Gene_expression (expressed) of muR in embryonic kidney associated with opioid receptor
3) Confidence 0.03 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7561859 Disease Relevance 0 Pain Relevance 0.31
To test this hypothesis, myc-tagged ORL1 and HA-tagged muR are co-expressed in human embryonic kidney (HEK) 293 cells.
Gene_expression (co-expressed) of muR in embryonic kidney
4) Confidence 0.03 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 15748148 Disease Relevance 0.09 Pain Relevance 0.53

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox