INT49508

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 1995
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 4.28
Pain Relevance 1.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ltb4r1) plasma membrane (Ltb4r1) signal transducer activity (Ltb4r1)
Anatomy Link Frequency
paw 1
Ltb4r1 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 1 99.92 Very High Very High Very High
Serotonin 7 98.96 Very High Very High Very High
Pain threshold 1 97.96 Very High Very High Very High
Inflammation 102 97.64 Very High Very High Very High
Hyperalgesia 1 93.60 High High
corticosteroid 65 87.84 High High
Analgesic 3 84.76 Quite High
antagonist 14 81.84 Quite High
Osteoarthritis 3 75.20 Quite High
Antinociceptive 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Occupational Lung Diseases 270 100.00 Very High Very High Very High
Pain 2 97.96 Very High Very High Very High
INFLAMMATION 107 97.64 Very High Very High Very High
Hyperalgesia 2 93.60 High High
Asthma 110 90.84 High High
Rhinitis 20 90.28 High High
Necrosis 1 86.36 High High
Cancer 1 86.00 High High
Osteoarthritis 3 75.20 Quite High
Inflammatory Pain 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exhaled LTB4 concentrations were detected in all steroid-naïve atopic asthmatics, atopic nonasthmatics, and healthy children and were undetectable in 7 steroid-treated atopic asthmatic children (Figure 2).
Regulation (undetectable) of LTB4 associated with occupational lung diseases
1) Confidence 0.18 Published 2005 Journal Respir Res Section Body Doc Link PMC1283153 Disease Relevance 0.47 Pain Relevance 0.03
This compound was effective on PGE2, LTB4, bradykinin, PAF or IL-1 beta-induced decrease in pain threshold in the rat paw pressure model and almost totally suppressed the writhing induced by zymosan in mice, while peritoneal production of 6-ketoPGF1 alpha was inhibited by 48.5-62% and only at 100 mg/kg significant inhibition of LTC4 was achieved.
Regulation (effective) of LTB4 in paw associated with pain threshold and bradykinin
2) Confidence 0.16 Published 1995 Journal Life Sci. Section Abstract Doc Link 7564876 Disease Relevance 0.53 Pain Relevance 0.57
The effect of allergen challenge on exhaled LTB4 levels in atopic asthmatic children is unknown and needs to be clarified.
Regulation (effect) of LTB4 associated with occupational lung diseases
3) Confidence 0.11 Published 2005 Journal Respir Res Section Body Doc Link PMC1283153 Disease Relevance 1.02 Pain Relevance 0.10
LTB4 values in EBC were expressed as total amount (in picograms) of leukotriene expired in the 15-minute breath test (LT concentrations × volume of EBC).
Regulation (values) of LTB4
4) Confidence 0.11 Published 2005 Journal Respir Res Section Body Doc Link PMC1283153 Disease Relevance 0 Pain Relevance 0
LTB4 values were expressed as the total amount (in pg) of eicosanoid expired in the 15-minute breath test.
Regulation (values) of LTB4
5) Confidence 0.11 Published 2005 Journal Respir Res Section Abstract Doc Link PMC1283153 Disease Relevance 0.73 Pain Relevance 0.15
We did not study the effects of allergen challenge on exhaled LTB4 in atopic nonasthmatic children and atopic asthmatic children.
Neg (not) Regulation (effects) of LTB4 associated with occupational lung diseases
6) Confidence 0.11 Published 2005 Journal Respir Res Section Body Doc Link PMC1283153 Disease Relevance 0.94 Pain Relevance 0.09
TNF-alpha, IL-1beta and LTB4 levels did not change.
Neg (not) Regulation (change) of LTB4
7) Confidence 0.01 Published 2008 Journal Rheumatol. Int. Section Abstract Doc Link 18368410 Disease Relevance 0.60 Pain Relevance 0.71

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox