INT4953

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Context Info
Confidence 0.60
First Reported 1990
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 16
Total Number 16
Disease Relevance 7.63
Pain Relevance 2.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cerebral spinal fluid 1
urine 1
CGB5 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 2 99.40 Very High Very High Very High
narcan 18 99.02 Very High Very High Very High
headache 1 98.42 Very High Very High Very High
abdominal pain 6 96.60 Very High Very High Very High
Opioid 7 95.76 Very High Very High Very High
Pain 9 85.16 High High
imagery 1 81.92 Quite High
Central nervous system 1 77.76 Quite High
antagonist 3 66.84 Quite High
cva 2 24.88 Low Low
Disease Link Frequency Relevance Heat
Sarcoma 3 99.84 Very High Very High Very High
Metrorrhagia 2 99.84 Very High Very High Very High
Germinoma 5 99.56 Very High Very High Very High
Cancer 15 99.44 Very High Very High Very High
Leiomyosarcoma 9 99.24 Very High Very High Very High
Reprotox - General 1 12 98.48 Very High Very High Very High
Headache 1 98.42 Very High Very High Very High
Adenocarcinoma 2 98.08 Very High Very High Very High
Rupture 2 97.40 Very High Very High Very High
Dislocations 1 97.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A 15-year-old boy with headaches and visual changes was diagnosed with a pineal germinoma by biopsy and mildly elevated beta-human chorionic gonadatropin (beta-HCG) in serum and cerebral spinal fluid.
Positive_regulation (elevated) of beta-HCG in cerebral spinal fluid associated with germinoma and headache
1) Confidence 0.60 Published 2009 Journal J. Pediatr. Hematol. Oncol. Section Abstract Doc Link 19779380 Disease Relevance 0.88 Pain Relevance 0.14
Beta-HCG is usually increased in germ-cell tumors but few reports in the literature describe beta-HCG-secreting leiomyosarcomas.
Positive_regulation (increased) of Beta-HCG associated with leiomyosarcoma and cancer
2) Confidence 0.59 Published 2002 Journal Am. J. Med. Sci. Section Abstract Doc Link 12186103 Disease Relevance 0.69 Pain Relevance 0.08
Serum beta-human chorionic gonadotropin (beta-HCG) was serially increased (19.71-22.71 mIU/mL).
Positive_regulation (increased) of beta-HCG
3) Confidence 0.59 Published 2002 Journal Am. J. Med. Sci. Section Abstract Doc Link 12186103 Disease Relevance 0.64 Pain Relevance 0.08
The incidence of increased levels of beta-HCG in sarcomas in general, and its potential role as a tumor marker, is not known.
Positive_regulation (increased) of beta-HCG associated with sarcoma and cancer
4) Confidence 0.59 Published 2002 Journal Am. J. Med. Sci. Section Abstract Doc Link 12186103 Disease Relevance 0.70 Pain Relevance 0.07
A strongly positive immunohistochemical staining for beta- subunit of human chorionic gonadotropin (beta-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum beta-HCG levels confirmed the diagnosis.
Positive_regulation (elevated) of beta-HCG
5) Confidence 0.56 Published 2009 Journal Indian J Pathol Microbiol Section Abstract Doc Link 19805966 Disease Relevance 0.85 Pain Relevance 0.12
-HCG levels are elevated [8].
Positive_regulation (elevated) of HCG
6) Confidence 0.45 Published 2008 Journal Cases J Section Body Doc Link PMC2621128 Disease Relevance 0.93 Pain Relevance 0.08
Postoperatively urine and serum had very high levels of beta-human chorionic gonogotrophins (B-HCG).
Positive_regulation (levels) of B-HCG in urine
7) Confidence 0.41 Published 2000 Journal Indian J Pathol Microbiol Section Abstract Doc Link 11344617 Disease Relevance 0.35 Pain Relevance 0.09
The serum beta-HCG level was markedly elevated, at 82,000 (normally less than 5) IU/L.
Positive_regulation (elevated) of serum beta-HCG
8) Confidence 0.35 Published 1991 Journal Can. J. Ophthalmol. Section Abstract Doc Link 1751915 Disease Relevance 0.48 Pain Relevance 0.16
Laboratory examinations revealed markedly high levels of LDH, AFP and HCG-beta.
Positive_regulation (levels) of HCG-beta
9) Confidence 0.34 Published 1990 Journal Hinyokika Kiyo Section Abstract Doc Link 1700589 Disease Relevance 0.73 Pain Relevance 0.10
The serum hCG level returned to normal 1 month after the operation, while an additional 2 months were necessary for the beta-hCG level to normalize.
Positive_regulation (normalize) of hCG
10) Confidence 0.27 Published 2000 Journal Jpn. J. Clin. Oncol. Section Abstract Doc Link 10798545 Disease Relevance 0.64 Pain Relevance 0.07
[Variations in the testicular response to HCG during the perinatal period in the rat: influence of estrogens].
Positive_regulation (response) of HCG associated with anesthesia
11) Confidence 0.12 Published 1992 Journal Arch Int Physiol Biochim Biophys Section Title Doc Link 1282394 Disease Relevance 0 Pain Relevance 0.18
Eight hours after hCG, prostaglandin content increased (P < 0.01) and remained high until 12 hours after hCG (P < 0.001).
Positive_regulation (increased) of hCG
12) Confidence 0.02 Published 1995 Journal Prostaglandins Section Abstract Doc Link 7480800 Disease Relevance 0 Pain Relevance 0.09
Naloxone alone was ineffective although it significantly enhanced hCG stimulated T release. beta-EP decreased both basal and hCG stimulated T release.
Positive_regulation (stimulated) of hCG associated with narcan
13) Confidence 0.01 Published 1995 Journal Indian J. Exp. Biol. Section Abstract Doc Link 7601485 Disease Relevance 0 Pain Relevance 0.38
Naloxone alone was ineffective although it significantly enhanced hCG stimulated T release. beta-EP decreased both basal and hCG stimulated T release.
Positive_regulation (stimulated) of hCG associated with narcan
14) Confidence 0.01 Published 1995 Journal Indian J. Exp. Biol. Section Abstract Doc Link 7601485 Disease Relevance 0 Pain Relevance 0.38
Naloxone alone was ineffective although it significantly enhanced hCG stimulated T release. beta-EP decreased both basal and hCG stimulated T release.
Positive_regulation (enhanced) of hCG associated with narcan
15) Confidence 0.01 Published 1995 Journal Indian J. Exp. Biol. Section Abstract Doc Link 7601485 Disease Relevance 0 Pain Relevance 0.38
Immunoperoxidase stain was strongly positive for hCG and a raised serum beta-hCG level preoperatively confirmed the diagnosis.
Positive_regulation (positive) of hCG
16) Confidence 0.01 Published 1991 Journal Eur. J. Gynaecol. Oncol. Section Abstract Doc Link 1915465 Disease Relevance 0.74 Pain Relevance 0.09

General Comments

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