INT49557

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Context Info
Confidence 0.02
First Reported 1995
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 8
Disease Relevance 16.54
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NOLC1) mitosis (NOLC1) nucleolus (NOLC1)
nucleus (NOLC1) cell cycle (NOLC1) DNA binding (NOLC1)
Anatomy Link Frequency
brains 1
basal ganglia 1
cortex 1
white matter 1
NOLC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 64 98.44 Very High Very High Very High
alcohol 10 86.00 High High
Central nervous system 15 73.28 Quite High
Inflammation 22 61.04 Quite High
methadone 1 50.00 Quite Low
anesthesia 5 23.20 Low Low
ketamine 5 22.40 Low Low
Inflammatory response 10 20.40 Low Low
Neurobehavioral 35 12.96 Low Low
cytokine 55 7.44 Low Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 1250 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 593 99.32 Very High Very High Very High
Cirrhosis 55 98.76 Very High Very High Very High
Viremia 26 97.92 Very High Very High Very High
Fibrosis 46 96.88 Very High Very High Very High
Disease 51 91.40 High High
Infection 215 91.12 High High
Immunodeficiency 2 90.64 High High
Cognitive Disorder 10 90.28 High High
Frailty 5 85.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HCV transcripts and proteins have also been detected in brains from HIV/HCV co-infected patients, indicating that HCV is neuroinvasive [9], [10], [11].
Transcription (transcripts) of HCV in brains associated with acquired immune deficiency syndrome or hiv infection and hepatitis c virus infection
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 2.57 Pain Relevance 0.07
HCV-encoded RNA was not detected in control groups and HIV/AIDS persons without HCV viremia.
Neg (not) Transcription (detected) of HCV associated with acquired immune deficiency syndrome or hiv infection, viremia and hepatitis c virus infection
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 2.58 Pain Relevance 0
Positive-strand HCV RNA was detectable in white matter, cortex and basal ganglia from the HIV/HCV co-infected patient at 102 viral copies/µg RNA, which were 10-fold lower than viral copy numbers in the matched spleen (Figure 1A).
Transcription (detectable) of HCV in white matter associated with acquired immune deficiency syndrome or hiv infection and hepatitis c virus infection
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 2.48 Pain Relevance 0
Compared with those without HIV, coinfected patients have higher HCV RNA levels and more rapid progression of hepatic fibrosis [16].
Transcription (levels) of HCV associated with fibrosis, cirrhosis, acquired immune deficiency syndrome or hiv infection and hepatitis c virus infection
4) Confidence 0.01 Published 2007 Journal Journal of Viral Hepatitis Section Body Doc Link PMC1974798 Disease Relevance 3.02 Pain Relevance 0.28
Patients with HCV genotypes 2 or 3 and baseline HCV RNA levels <800 000 IU/mL received only 24 weeks of treatment.
Transcription (levels) of HCV associated with hepatitis c virus infection
5) Confidence 0.01 Published 2007 Journal Journal of Viral Hepatitis Section Body Doc Link PMC1974798 Disease Relevance 0.76 Pain Relevance 0.03
HCV antibodies were detected in 84.2% of the sample and HCV RNA in 66.1% of the sample including 75.9% amongst those who were anti-HCV positive and 16.6% amongst those who were anti-HCV negative.
Transcription (detected) of HCV
6) Confidence 0.01 Published 1995 Journal N. Z. Med. J. Section Body Doc Link 7566775 Disease Relevance 0.15 Pain Relevance 0
Positive-strand HCV RNA was detectable in white matter, cortex and basal ganglia from the HIV/HCV co-infected patient at 102 viral copies/µg RNA, which were 10-fold lower than viral copy numbers in the matched spleen (Figure 1A).
Transcription (detectable) of HCV in basal ganglia associated with acquired immune deficiency syndrome or hiv infection and hepatitis c virus infection
7) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 2.48 Pain Relevance 0
Positive-strand HCV RNA was detectable in white matter, cortex and basal ganglia from the HIV/HCV co-infected patient at 102 viral copies/µg RNA, which were 10-fold lower than viral copy numbers in the matched spleen (Figure 1A).
Transcription (detectable) of HCV in cortex associated with acquired immune deficiency syndrome or hiv infection and hepatitis c virus infection
8) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943470 Disease Relevance 2.48 Pain Relevance 0

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