INT49676

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Context Info
Confidence 0.48
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 13
Disease Relevance 9.09
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TG) extracellular space (TG) extracellular region (TG)
Golgi apparatus (TG) endoplasmic reticulum (TG)
Anatomy Link Frequency
thyroid 2
TG (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 67 88.28 High High
Earache 1 81.88 Quite High
headache 4 80.92 Quite High
Inflammation 42 69.80 Quite High
excitatory amino acid 1 43.24 Quite Low
palliative 8 39.52 Quite Low
cva 3 36.72 Quite Low
withdrawal 52 31.00 Quite Low
agonist 51 5.00 Very Low Very Low Very Low
Pain 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 761 99.64 Very High Very High Very High
Recurrence 95 99.60 Very High Very High Very High
Metastasis 233 98.88 Very High Very High Very High
Disease 500 98.32 Very High Very High Very High
Thyroiditis 1 98.32 Very High Very High Very High
Pathologic Constriction 2 96.16 Very High Very High Very High
Cancer 607 94.80 High High
Apoptosis 21 94.12 High High
Cicatrix 1 92.00 High High
Malignant Neoplastic Disease 82 90.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For those patients with elevated thyroglobulin and a negative iodine scan, PET/CT is exceptionally helpful in identifying recurrent and distant disease and has been shown to provide important prognostic information.
Positive_regulation (elevated) of thyroglobulin associated with disease
1) Confidence 0.48 Published 2010 Journal Journal of Thyroid Research Section Body Doc Link PMC2956973 Disease Relevance 1.00 Pain Relevance 0
The serum thyroglobulin concentration was markedly elevated (1011 ng/mL).
Positive_regulation (elevated) of thyroglobulin
2) Confidence 0.47 Published 1995 Journal Thyroid Section Abstract Doc Link 7580271 Disease Relevance 0.74 Pain Relevance 0.13
Thyroglobulin level increased in 1 (17%) out of 6 evaluable patients with 13-CRA RDT-induced 131-I uptake and in 12 (34%) out of 35 without radioiodine uptake on rxWBS (p > 0.05).
Positive_regulation (increased) of Thyroglobulin
3) Confidence 0.46 Published 2009 Journal Thyroid Res Section Body Doc Link PMC2739165 Disease Relevance 0 Pain Relevance 0
An elevated anti-thyroglobulin antibody titer indicated the presence of autoimmune thyroiditis.
Positive_regulation (elevated) of anti-thyroglobulin associated with thyroiditis
4) Confidence 0.40 Published 2006 Journal Intern. Med. Section Abstract Doc Link 17139127 Disease Relevance 0.34 Pain Relevance 0.20
Low risk patients can usually be evaluated by recombinant TSH (Thyrogen) stimulated thyroglobulin levels avoiding the need for an iodine scan.
Positive_regulation (stimulated) of thyroglobulin
5) Confidence 0.35 Published 2010 Journal Journal of Thyroid Research Section Body Doc Link PMC2956973 Disease Relevance 0.95 Pain Relevance 0
In spite of the complication rate, when a subtotal thyroidectomy is performed for the management of thyroid carcinoma, it becomes difficult to follow thyroglobulin levels for surveillance [43].
Positive_regulation (follow) of thyroglobulin in thyroid associated with thyroid neoplasm
6) Confidence 0.32 Published 2010 Journal Journal of Thyroid Research Section Body Doc Link PMC2956973 Disease Relevance 0.39 Pain Relevance 0
Since the majority of recurrences occur in the thyroid bed, neck ultrasonography represents the most sensitive means for detecting recurrence in the presence of elevated thyroglobulin.
Positive_regulation (elevated) of thyroglobulin in thyroid associated with recurrence
7) Confidence 0.32 Published 2010 Journal Journal of Thyroid Research Section Body Doc Link PMC2956973 Disease Relevance 0.95 Pain Relevance 0
This patient also presented with an elevated serum thyroglobulin (Tg) (707 ng/ml) without thyroglobulin antibody (TgAb) under TSH suppression (0.025 ?
Positive_regulation (elevated) of thyroglobulin
8) Confidence 0.22 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2765443 Disease Relevance 0.92 Pain Relevance 0
Most of these patients had markedly elevated serum thyroglobulin levels and negative 123I scans.
Positive_regulation (elevated) of thyroglobulin
9) Confidence 0.21 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.17 Pain Relevance 0.11
had elevated serum thyroglobulin levels and negative radioiodine scans [95].
Positive_regulation (elevated) of thyroglobulin
10) Confidence 0.20 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 0.65 Pain Relevance 0
elevated thyroglobulin whereas others had diffuse metastases), dose level,
Positive_regulation (elevated) of thyroglobulin associated with metastasis
11) Confidence 0.14 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 0.94 Pain Relevance 0
for one month, then 8 mg/day for 2 months), thyroglobulin levels increased in 4
Positive_regulation (increased) of thyroglobulin
12) Confidence 0.14 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 0.88 Pain Relevance 0
1–40 is formed in the transgolgi network (TGN) while A?
Positive_regulation (formed) of TGN
13) Confidence 0.04 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656296 Disease Relevance 0.15 Pain Relevance 0

General Comments

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