INT49712

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.28
First Reported 1995
Last Reported 2010
Negated 0
Speculated 2
Reported most in Abstract
Documents 10
Total Number 12
Disease Relevance 5.65
Pain Relevance 4.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Nr3c1) intracellular (Nr3c1) DNA binding (Nr3c1)
protein complex (Nr3c1) cytoplasm (Nr3c1) cytosol (Nr3c1)
Anatomy Link Frequency
hippocampus 3
blood 1
brain 1
frontal cortex 1
Nr3c1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antidepressant 15 100.00 Very High Very High Very High
antagonist 9 100.00 Very High Very High Very High
withdrawal 6 100.00 Very High Very High Very High
opiate 4 100.00 Very High Very High Very High
addiction 3 100.00 Very High Very High Very High
electroacupuncture 91 99.96 Very High Very High Very High
Hippocampus 27 99.28 Very High Very High Very High
qutenza 7 98.50 Very High Very High Very High
depression 25 98.40 Very High Very High Very High
fluoxetine 9 97.92 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 97 100.00 Very High Very High Very High
Opiate Addiction 4 100.00 Very High Very High Very High
Pressure And Volume Under Development 20 99.64 Very High Very High Very High
Stroke 27 99.62 Very High Very High Very High
Disease 6 99.48 Very High Very High Very High
Depression 26 98.40 Very High Very High Very High
Urological Neuroanatomy 9 97.68 Very High Very High Very High
INFLAMMATION 31 85.48 High High
Anxiety Disorder 6 84.56 Quite High
Wound Healing 68 84.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, in the present study we investigated the effect of prenatal stress on behavioral changes, blood corticosterone level, concentrations of glucocorticoid receptor (GR) and its cochaperone, FKBP51, in the hippocampus and frontal cortex in adult rats.
Spec (investigated) Regulation (effect) of glucocorticoid receptor in frontal cortex associated with stress, urological neuroanatomy and hippocampus
1) Confidence 0.28 Published 2009 Journal Psychoneuroendocrinology Section Abstract Doc Link 19195790 Disease Relevance 0.86 Pain Relevance 0.21
Differential regulation of variant glucocorticoid receptor mRNAs in the rat hippocampus by the antidepressant fluoxetine.
Regulation (regulation) of glucocorticoid receptor in hippocampus associated with antidepressant, hippocampus and fluoxetine
2) Confidence 0.26 Published 2004 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 15469896 Disease Relevance 0 Pain Relevance 0.51
These results suggest that prolonged glucocorticoid receptor (GR) occupation in the neonatal period leads to permanent alterations in ORL1 expression in the LHPA stress axis of the adult rat.
Regulation (prolonged) of glucocorticoid receptor associated with stress
3) Confidence 0.23 Published 2003 Journal Brain Res. Dev. Brain Res. Section Abstract Doc Link 14643007 Disease Relevance 0.28 Pain Relevance 0.43
The effects of desensitization of capsaicin-sensitive afferent neurons on the microcirculation in the stomach in rats depend on the blood glucocorticoid hormone level.
Regulation (depend) of glucocorticoid hormone in blood associated with qutenza
4) Confidence 0.23 Published 2009 Journal Neurosci. Behav. Physiol. Section Title Doc Link 19517242 Disease Relevance 0 Pain Relevance 0.50
The effect of antidepressant drugs on the HPA axis activity, glucocorticoid receptor level and FKBP51 concentration in prenatally stressed rats.
Regulation (effect) of glucocorticoid receptor associated with antidepressant
5) Confidence 0.17 Published 2009 Journal Psychoneuroendocrinology Section Title Doc Link 19195790 Disease Relevance 0.73 Pain Relevance 0.20
Studies have demonstrated that long-term changes in 5-HT levels are associated with alterations in hippocampal glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) number.
Regulation (alterations) of glucocorticoid receptor
6) Confidence 0.16 Published 1995 Journal Brain Res. Section Abstract Doc Link 7583200 Disease Relevance 0 Pain Relevance 0.30
Experiment 3 was to determine whether a prototypical glucocorticoid receptor antagonist, RU486, affects EA anti-edema.
Regulation (affects) of glucocorticoid receptor associated with pressure and volume under development, antagonist and electroacupuncture
7) Confidence 0.14 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC1976320 Disease Relevance 0.41 Pain Relevance 0.75
Because GC therapy also represents a potential treatment for stroke, investigation of glucocorticoid receptor (GR) regulation is critical to explore potential therapeutic avenues.
Regulation (regulation) of glucocorticoid receptor associated with stroke
8) Confidence 0.10 Published 2010 Journal Exp Transl Stroke Med Section Body Doc Link PMC2954925 Disease Relevance 1.21 Pain Relevance 0.03
Therefore, in the present study we investigated the effect of prenatal stress on behavioral changes, blood corticosterone level, concentrations of glucocorticoid receptor (GR) and its cochaperone, FKBP51, in the hippocampus and frontal cortex in adult rats.
Spec (investigated) Regulation (effect) of glucocorticoid receptor in hippocampus associated with stress, urological neuroanatomy and hippocampus
9) Confidence 0.10 Published 2009 Journal Psychoneuroendocrinology Section Abstract Doc Link 19195790 Disease Relevance 0.86 Pain Relevance 0.21
The hippocampus appears to mediate this effect, through changes in the hippocampal glucocorticoid receptor (GR) induced by differences in rat maternal attachment behaviors (licking and grooming) [2].
Regulation (changes) of glucocorticoid receptor in hippocampus associated with hippocampus
10) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2677672 Disease Relevance 0.34 Pain Relevance 0.13
The effects of opiate dependence and antagonist-precipitated withdrawal on glucocorticoid (GR) and mineralocorticoid (MR) receptor mRNA levels in the rat brain were studied.
Regulation (effects) of glucocorticoid in brain associated with addiction, antagonist, opiate and withdrawal
11) Confidence 0.06 Published 2003 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 14559365 Disease Relevance 0.17 Pain Relevance 0.69
Depletion of HSP70 messenger ribonucleic acid has been observed in some depressed patients, but not in control subjects or in patients with other diseases.3 HSP70 is also known to control the glucocorticoid receptor (GR), which is known to play a role in depression.4,5
Regulation (control) of glucocorticoid receptor associated with depression and disease
12) Confidence 0.04 Published 2010 Journal Psychiatry Investigation Section Body Doc Link PMC2848765 Disease Relevance 0.78 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox