INT49846

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Context Info
Confidence 0.24
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.31
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (HBS1L) translation (HBS1L) GTPase activity (HBS1L)
Anatomy Link Frequency
hepatocytes 1
HBS1L (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 10 98.32 Very High Very High Very High
excitatory amino acid 2 88.48 High High
headache 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 21 95.12 Very High Very High Very High
Hepatitis B Virus Infection 75 86.88 High High
Liver Failure 5 85.92 High High
Malaria 58 85.04 High High
Recurrence 18 84.08 Quite High
Thalassemia 4 78.56 Quite High
Death 1 50.64 Quite High
Leishmaniasis 8 49.52 Quite Low
Falciparum Malaria 3 37.84 Quite Low
Anaemia 4 24.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The impact of endogamy on the segregation of HbS and similar traits needs to be carefully examined given the existing contrasting views on its impact on these variants.
Localization (segregation) of HbS
1) Confidence 0.24 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2829010 Disease Relevance 0.35 Pain Relevance 0
When the ERFs of tectal cells were localized outside the ERF of the isthmic cell where the chemical was injected, Imc-injected lidocaine had no effect in 9 out of 10 tectal cells, whereas Ipc-injected NMDA increased firing in 7 out of 17 tectal cells.
Localization (localized) of ERFs associated with lidocaine
2) Confidence 0.11 Published 1995 Journal Exp Brain Res Section Abstract Doc Link 7589290 Disease Relevance 0 Pain Relevance 0.44
Micro-injections of lidocaine into Imc resulted in a significant reduction of firing rate in 80% of tectal cells, whose excitatory receptive fields (ERFs) were localized within the ERF of the Imc cell where the lidocaine was injected.
Localization (localized) of ERFs associated with lidocaine
3) Confidence 0.11 Published 1995 Journal Exp Brain Res Section Abstract Doc Link 7589290 Disease Relevance 0 Pain Relevance 0.42
Anti-HBs also undergoes endocytosis by hepatocytes and binds to HBsAg within cells already infected, thereby decreasing HBsAg secretion.
Localization (secretion) of HBsAg in hepatocytes
4) Confidence 0.02 Published 2006 Journal Ann Clin Microbiol Antimicrob Section Body Doc Link PMC1459192 Disease Relevance 0.96 Pain Relevance 0

General Comments

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