INT49899

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Context Info
Confidence 0.43
First Reported 1994
Last Reported 1995
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.17
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Man2a2)
Anatomy Link Frequency
skeletal muscle 2
Man2a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 1 83.56 Quite High
tetrodotoxin 1 78.80 Quite High
Sciatic nerve 1 77.04 Quite High
Kinase C 4 75.00 Quite High
Serotonin 2 75.00 Quite High
antagonist 2 75.00 Quite High
Clonidine 3 70.28 Quite High
monoamine 1 63.80 Quite High
agonist 1 47.96 Quite Low
Disease Link Frequency Relevance Heat
Paralysis 1 91.52 High High
Shock 1 78.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Idazoxan and mianserin did not affect the responsiveness of the postsynaptic 5-HT1A and alpha-2 adrenergic receptors as indicated by the unchanged suppressant effects of microiontophoretically applied 5-HT and NE.
Neg (not) Regulation (affect) of Regulation (responsiveness) of alpha-2
1) Confidence 0.43 Published 1994 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7912278 Disease Relevance 0.08 Pain Relevance 0.32
We investigated the roles of electrical activity and trophic factors in the regulation of the genes encoding the alpha 1, alpha 2, and beta subunits of the DHP receptor as well as the RY receptor in rat skeletal muscle in vivo.
Spec (investigated) Regulation (roles) of Regulation (regulation) of alpha 2 in skeletal muscle
2) Confidence 0.02 Published 1995 Journal J. Biol. Chem. Section Abstract Doc Link 7592768 Disease Relevance 0.09 Pain Relevance 0.15

General Comments

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