INT49908

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Context Info
Confidence 0.45
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.32
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (RYR1) transmembrane transport (RYR1) cytoplasm (RYR1)
Anatomy Link Frequency
skeletal muscle 2
RYR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 4 98.56 Very High Very High Very High
tetrodotoxin 1 73.32 Quite High
Sciatic nerve 1 72.44 Quite High
anesthesia 23 5.00 Very Low Very Low Very Low
halothane 15 5.00 Very Low Very Low Very Low
sodium channel 5 5.00 Very Low Very Low Very Low
Calcium channel 3 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Hyperthermia 169 92.96 High High
Paralysis 1 79.68 Quite High
Mental Disorders 20 50.00 Quite Low
Chronic Disease 12 39.12 Quite Low
Central Core Disease 22 39.00 Quite Low
Phobia 1 23.24 Low Low
Syndrome 21 5.00 Very Low Very Low Very Low
Muscle Rigidity 18 5.00 Very Low Very Low Very Low
Fever 16 5.00 Very Low Very Low Very Low
Hyperkalemia 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interpretation of risk for other family members in the context of RYR1 analysis
Regulation (context) of Gene_expression (analysis) of RYR1
1) Confidence 0.45 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1867813 Disease Relevance 0.24 Pain Relevance 0
Electronic MHS records
Regulation (Electronic) of Gene_expression (records) of MHS
2) Confidence 0.39 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1949813 Disease Relevance 0 Pain Relevance 0
Regulation of dihydropyridine and ryanodine receptor gene expression in skeletal muscle.
Regulation (Regulation) of Gene_expression (expression) of ryanodine receptor in skeletal muscle
3) Confidence 0.00 Published 1995 Journal J. Biol. Chem. Section Title Doc Link 7592768 Disease Relevance 0.08 Pain Relevance 0.19

General Comments

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