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Context Info
Confidence 0.29
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.74
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger3)
Anatomy Link Frequency
2B5 2
Ptger3 (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 29 86.08 High High
bradykinin 1 66.08 Quite High
Pain 5 64.56 Quite High
agonist 1 57.64 Quite High
antagonist 1 53.84 Quite High
midbrain 1 51.00 Quite High
Thalamus 2 50.60 Quite High
Hippocampus 8 50.20 Quite High
cerebral cortex 1 49.68 Quite Low
spinal dorsal horn 1 47.44 Quite Low
Disease Link Frequency Relevance Heat
Fever 3 92.72 High High
Targeted Disruption 17 82.96 Quite High
Nociception 2 78.32 Quite High
Pain 3 64.56 Quite High
Hypercalcemia 1 29.68 Quite Low
Cancer 1 22.64 Low Low
Hypertension 1 18.64 Low Low
Disease 2 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The addition of 2B5 to [3H]PGE2 blocked the binding of radioligand to cell membranes transfected with the murine EP3 prostaglandin receptor.
Positive_regulation (transfected) of Gene_expression (transfected) of EP3 prostaglandin receptor in 2B5
1) Confidence 0.29 Published 1995 Journal J. Immunol. Section Abstract Doc Link 7594605 Disease Relevance 0.14 Pain Relevance 0.03
An in situ hybridization study showed that EP3 mRNA is expressed at a particularly high level in the regions surrounding the OVLT (Sugimoto et al. 1994).
Positive_regulation (level) of Gene_expression (expressed) of EP3 mRNA in OVLT
2) Confidence 0.27 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759147 Disease Relevance 0.60 Pain Relevance 0.30

General Comments

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