INT49942

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Context Info
Confidence 0.02
First Reported 1995
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.24
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Pdx1) cytosol (Pdx1) nucleus (Pdx1)
DNA binding (Pdx1) transcription factor binding (Pdx1) cytoplasm (Pdx1)
Anatomy Link Frequency
proximal 1
Pdx1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 3 87.80 High High
Enkephalin 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Sprains And Strains 6 94.88 High High
Stress 3 93.68 High High
Toxicity 6 88.80 High High
Pheochromocytoma 2 67.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The soxS promoter was strongly induced by 4-aminophenol and 2-aminophenol.
Positive_regulation (induced) of soxS promoter
1) Confidence 0.02 Published 1997 Journal Mutagenesis Section Abstract Doc Link 9237764 Disease Relevance 0.39 Pain Relevance 0.08
Mutagenesis of the TH E1 sequence within the normal context of the TH gene proximal promoter leads to a 50% decrease in the cyclic AMP inducibility of the promoter.
Positive_regulation (inducibility) of promoter in proximal
2) Confidence 0.02 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7595476 Disease Relevance 0.07 Pain Relevance 0
The Escherichia coli soxS promoter, which is induced in the presence of redox cycling agents like paraquat, was induced weakly by aniline at toxic doses.
Positive_regulation (induced) of soxS promoter
3) Confidence 0.02 Published 1997 Journal Mutagenesis Section Abstract Doc Link 9237764 Disease Relevance 0.40 Pain Relevance 0.09
The Escherichia coli soxS promoter, which is induced in the presence of redox cycling agents like paraquat, was induced weakly by aniline at toxic doses.
Positive_regulation (induced) of soxS promoter
4) Confidence 0.02 Published 1997 Journal Mutagenesis Section Abstract Doc Link 9237764 Disease Relevance 0.38 Pain Relevance 0.09
PC12 cells transfected with a TH promoter-luciferase reporter gene showed a robust induction in response to butyrate that was significantly reduced after co-transfection of either of two dominant-negative CREB expression vectors.
Positive_regulation (induction) of promoter-luciferase
5) Confidence 0.00 Published 2006 Journal Brain Res. Section Abstract Doc Link 16854387 Disease Relevance 0 Pain Relevance 0

General Comments

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