INT49955

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Context Info
Confidence 0.21
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.31
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OPRM1, ADCY1) small molecule metabolic process (ADCY1) Golgi apparatus (OPRM1)
endoplasmic reticulum (OPRM1) GTPase activity (ADCY1) transmembrane transport (ADCY1)
OPRM1 (Homo sapiens)
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 14 100.00 Very High Very High Very High
Enkephalin 4 100.00 Very High Very High Very High
agonist 2 88.32 High High
Opioid 8 79.04 Quite High
Disease Link Frequency Relevance Heat
Bordatella Infection 6 73.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By using transient transfection studies, the ability of the cloned mu-opioid receptor to stimulate type II adenylyl cyclase was examined.
mu-opioid receptor Positive_regulation (stimulate) of cyclase associated with opioid receptor
1) Confidence 0.21 Published 1995 Journal J. Neurochem. Section Abstract Doc Link 7595566 Disease Relevance 0.13 Pain Relevance 0.52
Activation of type II adenylyl cyclase by the cloned mu-opioid receptor: coupling to multiple G proteins.
mu-opioid receptor Positive_regulation (Activation) of cyclase associated with enkephalin and opioid receptor
2) Confidence 0.21 Published 1995 Journal J. Neurochem. Section Title Doc Link 7595566 Disease Relevance 0.18 Pain Relevance 0.66

General Comments

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