INT50014

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Context Info
Confidence 0.27
First Reported 1994
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 1.59
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ARHGAP4) signal transduction (ARHGAP4) nucleolus (ARHGAP4)
nucleus (ARHGAP4) intracellular (ARHGAP4) cytoskeleton organization (ARHGAP4)
ARHGAP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nicotine 1 90.32 High High
Potency 1 87.60 High High
Central nervous system 1 76.96 Quite High
headache 3 74.96 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Vomiting 2 99.92 Very High Very High Very High
Colon Cancer 3 94.08 High High
Hypocalcemia 1 92.96 High High
Pressure And Volume Under Development 6 83.96 Quite High
Sprains And Strains 1 80.32 Quite High
Erythema 3 75.36 Quite High
Headache 3 74.96 Quite High
Chills 3 74.00 Quite High
Hereditary Angioedema 3 65.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recombinant gamma interferon (rHuIFN-gamma) has been recognized to increase mRNA and protein levels of C1 inhibitor (C1 INH) in various human cells.
Negative_regulation (inhibitor) of C1
1) Confidence 0.27 Published 1994 Journal J. Lab. Clin. Med. Section Abstract Doc Link 8301199 Disease Relevance 0.35 Pain Relevance 0.06
Recombinant gamma interferon (rHuIFN-gamma) has been recognized to increase mRNA and protein levels of C1 inhibitor (C1 INH) in various human cells.
Negative_regulation (inhibitor) of C1
2) Confidence 0.27 Published 1994 Journal J. Lab. Clin. Med. Section Abstract Doc Link 8301199 Disease Relevance 0.35 Pain Relevance 0.06
RGC induced by apomorphine was inhibited by pretreatment with E-CT as well as hexamethonium, atropine, or surgical vagotomy.
Negative_regulation (inhibited) of RGC
3) Confidence 0.27 Published 1995 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 7600451 Disease Relevance 0.37 Pain Relevance 0.13
Administration of gamma interferon in human subjects decreases plasminogen activation and fibrinolysis without influencing C1 inhibitor.
Negative_regulation (inhibitor) of C1
4) Confidence 0.20 Published 1994 Journal J. Lab. Clin. Med. Section Title Doc Link 8301199 Disease Relevance 0.53 Pain Relevance 0.07

General Comments

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