INT50016

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Context Info
Confidence 0.49
First Reported 1994
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.80
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ARHGAP4) signal transduction (ARHGAP4) nucleolus (ARHGAP4)
nucleus (ARHGAP4) intracellular (ARHGAP4) cytoskeleton organization (ARHGAP4)
Anatomy Link Frequency
plasma 1
ARHGAP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 74 100.00 Very High Very High Very High
Nicotine 1 88.00 High High
Potency 1 87.60 High High
antagonist 5 87.12 High High
Central nervous system 3 74.64 Quite High
headache 1 68.40 Quite High
nMDA receptor 6 37.36 Quite Low
Analgesic 1 25.00 Low Low
Glutamate receptor 5 7.92 Low Low
excitatory amino acid 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 4 99.96 Very High Very High Very High
Vomiting 2 99.92 Very High Very High Very High
Colon Cancer 1 99.90 Very High Very High Very High
Glaucoma 14 97.12 Very High Very High Very High
Hypocalcemia 1 92.96 High High
Pressure And Volume Under Development 3 86.40 High High
Nervous System Injury 1 83.68 Quite High
Sprains And Strains 1 80.32 Quite High
Injury 2 71.48 Quite High
Erythema 1 69.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
to increased vitreous glutamate levels and RGC death [33].
Positive_regulation (increased) of RGC associated with glutamate and death
1) Confidence 0.49 Published 2007 Journal Experimental Diabetes Research Section Body Doc Link PMC1940058 Disease Relevance 1.05 Pain Relevance 0.38
Further, when administered to patients with colon cancer, it increased plasma C1 INH levels.
Positive_regulation (increased) of C1 in plasma associated with colon cancer
2) Confidence 0.33 Published 1994 Journal J. Lab. Clin. Med. Section Abstract Doc Link 8301199 Disease Relevance 0.39 Pain Relevance 0.07
RGC induced by apomorphine was inhibited by pretreatment with E-CT as well as hexamethonium, atropine, or surgical vagotomy.
Positive_regulation (induced) of RGC
3) Confidence 0.29 Published 1995 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 7600451 Disease Relevance 0.37 Pain Relevance 0.13

General Comments

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