INT50037

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Context Info
Confidence 0.58
First Reported 1995
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 4.14
Pain Relevance 2.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il5) extracellular region (Il5)
Anatomy Link Frequency
monocytes 1
lymphocytes 1
Th2 cells 1
T lymphocytes 1
Il5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 35 99.42 Very High Very High Very High
aspirin 8 96.56 Very High Very High Very High
Arthritis 72 95.56 Very High Very High Very High
abdominal pain 2 95.16 Very High Very High Very High
carbamazepine 3 93.24 High High
lidocaine 8 88.96 High High
anticonvulsant 1 85.80 High High
complementary and alternative medicine 33 84.28 Quite High
Inflammatory mediators 4 80.96 Quite High
chemokine 10 80.64 Quite High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 5 99.98 Very High Very High Very High
Peritonitis 2 99.64 Very High Very High Very High
Rhinitis 2 99.40 Very High Very High Very High
Hypersensitivity 11 99.02 Very High Very High Very High
Vomiting 2 96.44 Very High Very High Very High
Diarrhoea 1 95.72 Very High Very High Very High
Arthritis 48 95.56 Very High Very High Very High
Abdominal Pain 2 95.16 Very High Very High Very High
Autoimmune Disease 18 91.60 High High
Necrosis 2 88.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A case of eosinophilic peritonitis in which ascites interleukin 5 presented at a high level.
Localization (presented) of interleukin 5 associated with pressure and volume under development, rhinitis and peritonitis
1) Confidence 0.58 Published 2000 Journal Hepatogastroenterology Section Title Doc Link 11149008 Disease Relevance 1.04 Pain Relevance 0.10
, whereas the counter-regulatory Th2 cells secrete IL-4, IL-5, IL-10, and IL-13 [118].
Localization (secrete) of IL-5 in Th2 cells
2) Confidence 0.06 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC3014691 Disease Relevance 1.15 Pain Relevance 0.40
In this study, we provide evidence that NCX-4016 delivered to PMBC-derived T lymphocytes and monocytes causes a transitory inhibition of cell respiration and approximately 50% reduction of cellular ATP, which translates in a time-reversible inhibition of cell proliferation and IL-2, IL-4, IL-5, and IFN-gamma secretion.
Localization (secretion) of IL-5 in monocytes
3) Confidence 0.04 Published 2004 Journal J. Immunol. Section Abstract Doc Link 15240674 Disease Relevance 0.07 Pain Relevance 0.28
In the late-phase allergic response, cytokines such as interleukin (IL)-4, IL-5, IL-6, IL-8, IL-13, and TNF are induced and secreted [30].
Localization (secreted) of IL-5 associated with hypersensitivity and cytokine
4) Confidence 0.04 Published 2005 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2877069 Disease Relevance 0.67 Pain Relevance 0.26
In addition, three CD4+ and all CD8+ (n = 7) clones secreted high IFN-gamma and low levels of IL-5/IL-4 (Th1-like).
Localization (secreted) of IL-5
5) Confidence 0.03 Published 1997 Journal J. Immunol. Section Abstract Doc Link 9013953 Disease Relevance 0.32 Pain Relevance 0.73
Drug-activated lymphocytes secreted high amounts of IL-5 and normal or low levels of IL-2, IFN-gamma, IL-4, and TNF-alpha.
Localization (secreted) of IL-5 in lymphocytes
6) Confidence 0.02 Published 1995 Journal J. Immunol. Section Abstract Doc Link 7602118 Disease Relevance 0.80 Pain Relevance 0.26
In this study, we provide evidence that NCX-4016 delivered to PMBC-derived T lymphocytes and monocytes causes a transitory inhibition of cell respiration and approximately 50% reduction of cellular ATP, which translates in a time-reversible inhibition of cell proliferation and IL-2, IL-4, IL-5, and IFN-gamma secretion.
Localization (secretion) of IL-5 in T lymphocytes
7) Confidence 0.01 Published 2004 Journal J. Immunol. Section Abstract Doc Link 15240674 Disease Relevance 0.07 Pain Relevance 0.28

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