INT50057

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Context Info
Confidence 0.39
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 0.87
Pain Relevance 2.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Notch1) Golgi apparatus (Notch1) plasma membrane (Notch1)
nucleus (Notch1) embryo development (Notch1) cytoplasm (Notch1)
Anatomy Link Frequency
Notch 2
Notch1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 8 100.00 Very High Very High Very High
agonist 4 100.00 Very High Very High Very High
Enkephalin 2 100.00 Very High Very High Very High
Analgesic 1 100.00 Very High Very High Very High
nociceptor 1 100.00 Very High Very High Very High
Morphine 12 99.80 Very High Very High Very High
antinociception 6 99.12 Very High Very High Very High
antagonist 4 56.80 Quite High
mu opioid receptor 1 49.60 Quite Low
Hippocampus 6 46.08 Quite Low
Disease Link Frequency Relevance Heat
Creutzfeldt Jakob Disease 36 99.84 Very High Very High Very High
Stress Incontinence 35 92.56 High High
Liver Disease 1 64.96 Quite High
Disease 29 41.44 Quite Low
Pressure And Volume Under Development 3 25.28 Quite Low
Attention Deficit Hyperactivity Disorder 1 15.00 Low Low
Body Weight 16 14.40 Low Low
Scrapie 23 5.00 Very Low Very Low Very Low
Sprains And Strains 9 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently it was reported that homocysteine is able to modulate Notch1 function by interacting with cystein bonds in the Notch receptor [50].
Regulation (modulate) of Notch1 in Notch
1) Confidence 0.39 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2699037 Disease Relevance 0.06 Pain Relevance 0
The hypothesis that the Notch-1 intracellular domain, NICD, is involved in prion disease was tested by treating prion-infected mice with the ?
Regulation (involved) of Notch-1 in Notch associated with creutzfeldt jakob disease
2) Confidence 0.12 Published 2010 Journal Mol Neurodegener Section Abstract Doc Link PMC2825502 Disease Relevance 0.81 Pain Relevance 0
Effects of a highly selective nonpeptide delta opioid receptor agonist, TAN-67, on morphine-induced antinociception in mice.
Regulation (Effects) of TAN-67 associated with antinociception, analgesic, agonist, opioid receptor and morphine
3) Confidence 0.12 Published 1995 Journal Life Sci. Section Title Doc Link 7603296 Disease Relevance 0 Pain Relevance 2.14

General Comments

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