INT50083

Context Info Confidence 0.01 First Reported 1995 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.01 Pain Relevance 0.15

transport (SLC12A1) plasma membrane (SLC12A1) transmembrane transport (SLC12A1)

Anatomy Link Frequency plasma 1 SLC12A1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 2 98.76 Pain 1 97.08 addiction 2 9.84 Restless leg syndrome 1 5.00 Migraine 1 5.00 endometriosis 1 5.00 psoriasis 1 5.00 rheumatoid arthritis 1 5.00 Osteoarthritis 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 2 99.94 Nervous System Injury 2 99.32 Crystal Associated Disease 8 97.44 Low Back Pain 1 97.36 Kidney Stones 19 86.64 Chronic Renal Failure 49 86.04 Disease 10 85.60 Prostate Or Kidney Disorder 9 47.32 Lifespan 1 38.48 Increased Venous Pressure Under Development 3 32.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Preliminary study of an increase of a plasma apolipoprotein E variant associated with peripheral nerve damage.

variant Binding (associated) of in plasma associated with nervous system injury, inflammation and disorder of lipid metabolism

1) Confidence 0.01 Published 1995 Journal Spine Section Title Doc Link 7604328 Disease Relevance 0.30 Pain Relevance 0.15

We demonstrate that this variant associates significantly with serum urea, uric acid and suggestively with gout.

variant Binding (associates) of associated with crystal associated disease

2) Confidence 0.00 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2912386 Disease Relevance 0.71 Pain Relevance 0

General Comments

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