INT50310

Context Info Confidence 0.20 First Reported 1995 Last Reported 1995 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0.28

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a) plasma membrane (Ptger2) signal transducer activity (Ptger2)

Il1a (Rattus norvegicus) Ptger2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Cannabinoid 4 99.40 Cannabinoid receptor 2 74.96 agonist 3 68.32 Clonidine 1 66.40 antagonist 2 55.60

Disease Link Frequency Relevance Heat Hypothermia 3 60.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the present study we have characterized the hypothermic effect of the psychoactive cannabinoid HU-210, by investigating its interaction with the endogenous pyrogens, IL-1 and PGE2.

IL-1 Binding (interaction) of PGE2 associated with cannabinoid

1) Confidence 0.20 Published 1995 Journal Neuropharmacology Section Abstract Doc Link 7617143 Disease Relevance 0.06 Pain Relevance 0.28

General Comments

This test has worked.